| Name | Mu opioid receptor |
|---|---|
| Synonyms | MOR 1; MOR1; Mu opiate receptor; Mu opioid receptor; Mu type opioid receptor; OPRM; OPRM 1; OPRM1… |
| Name | chloralose |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 8780231 | Bereiter DA, Benetti AP, Bereiter DF, Hathaway CB: Central trigeminal effects of somatostatin and etorphine on and autonomic function in the cat. Am J Physiol. 1996 Mar;270(3 Pt 2):R636-44. The influence of somatostatin and the potent mu-opiate receptor agonist etorphine on and autonomic responses mediated by trigeminal neurons was examined in chloralose-anesthetized cats. |
82(1,1,1,2) | Details |
| 15576661 | Cao WH, Morrison SF: Brown adipose tissue thermogenesis contributes to -evoked hyperthermia. Am J Physiol Regul Integr Comp Physiol. 2005 Mar;288(3):R723-32. Epub 2004 Dec 2. Mu-opioid receptor activation increases body temperature and affects cardiovascular function. In the present study, was administered intravenously [100 mug/kg (300 nmol/kg) iv] and intracerebroventricularly [3.4 mug (10 nmol) in 10 microl icv] in urethane-chloralose-anesthetized, artificially ventilated rats. |
3(0,0,0,3) | Details |
| 7589306 | Sato A, Sato Y, Schmidt RF: Modulation of somatocardiac sympathetic reflexes mediated by opioid receptors at the spinal and brainstem level. Exp Brain Res. 1995;105(1):1-6. Modulation of somatosympathetic reflexes at the spinal cord and the brainstem was studied by administering opioid receptor agonists into the intrathecal space of the lumbar spinal cord and into the subarachnoid space of the cisterna magna in rats anesthetized with alpha-chloralose and urethane. Intrathecal administration of the mu-opioid receptor agonist DAMGO selectively depressed the C-reflex in a dose-dependent manner (minimum effective dose 10 ng), whereas the intrathecal injection of the delta-opioid receptor agonist DPDPE and the kappa-opioid receptor agonist U-50,488H only at doses of 10 micrograms and 100 micrograms, respectively, led to a significant depression of the C-reflex. |
2(0,0,0,2) | Details |
| 9878876 | Mazario J, Roza C, Herrero JF: The NSAID dexketoprofen trometamol is as potent as mu-opioids in the depression of wind-up and spinal cord nociceptive reflexes in normal rats. Brain Res. 1999 Jan 23;816(2):512-7. These effects were compared with those of the mu-opioid receptor agonist in normal animals. The experiments were performed in male Wistar rats anaesthetised with alpha-chloralose. |
1(0,0,0,1) | Details |
| 7916175 | Wang M, Xu W, He L: Mu opiate receptor antagonist blocks electroacupuncture inhibition on noxious blood pressure response in rabbits. Acupunct Electrother Res. 1994 Jan-Mar;19(1):3-9. A pressor blood pressure response was elicited by strong electric shock stimulation of the front paw in rabbits anesthetized with chloralose and urethane, immobilized by gallamine triethiodide and maintained by artificial ventilation. |
1(0,0,0,1) | Details |
| 9274971 | Bradley KJ, Headley PM: Effect of on spinal nociceptive reflexes: lack of interaction with alpha2-adrenoceptor or mu-opioid receptor mechanisms. Eur J Pharmacol. 1997 Jul 23;331(2-3):133-8. has been tested i.v. in alpha-chloralose anaesthetised rats for its effects on spinal nociceptive reflexes evoked by mechanical and electrical stimuli. |
1(0,0,0,1) | Details |
| 15649868 | Crisostomo MM, Li P, Tjen-A-Looi SC, Longhurst JC: Nociceptin in rVLM mediates electroacupuncture inhibition of cardiovascular reflex excitatory response in rats. J Appl Physiol. 2005 Jun;98(6):2056-63. Epub 2005 Jan 13. Furthermore, a mu-opioid receptor agonist microinjected into the rVLM after microinjection of a nociceptin receptor antagonist during EA promptly reversed the nociceptin receptor antagonist-related inhibition of the EA effect. Blood pressure in ventilated male Sprague-Dawley rats (400-600 g) anesthetized by ketamine and alpha-chloralose was measured during balloon inflation of the stomach. |
1(0,0,0,1) | Details |
| 19041860 | Wojciechowski P, Szereda-Przestaszewska M, Lipkowski AW: Respiratory and cardiovascular effects of biphalin in anaesthetized rats. Eur J Pharmacol. 2009 Jan 5;602(1):50-3. Epub 2008 Nov 20. Biphalin (0.3 mg/kg) administered intravenously (i.v.) to urethane-chloralose anaesthetized rats consistently evoked apnoea, followed by breathing at subnormal respiratory rate with increased tidal volume. These results indicate that mu opioid receptors distributed in areas supplied by vagal afferents (e.g. the lung) are involved in respiratory and hypotensive effects of biphalin, whereas bradycardia may be explained by activation of brainstem regions mediating cardiovascular control. |
1(0,0,0,1) | Details |
| 9121816 | Sorkin LS, Puig S: Neuronal model of tactile allodynia produced by spinal strychnine: effects of excitatory amino acid receptor antagonists and a mu-opiate receptor agonist. Pain. 1996 Dec;68(2-3):283-92. In this study, we sought to characterize the effect of focal glycine-receptor inhibition on spontaneous and evoked activity in dorsal horn neurons of the chloralose-anesthetized cat. |
1(0,0,0,1) | Details |
| 7874523 | Thorn SA, Herrero JF, Headley PM: Stimulus intensity and the comparative efficacy of mu- and kappa-opioid agonists on nociceptive spinal reflexes in the rat. Brain Res. 1994 Nov 14;663(2):352-6. Spinal reflexes were generated by different intensities of noxious electrical stimuli in alpha-chloralose anaesthetized, spinalized rats. The results indicate that kappa-opioid receptor activation has similar potential for spinal analgesia as does activation of mu-opioid receptors. |
1(0,0,0,1) | Details |
| 18813049 | Teppema LJ, van Dorp E, Mousavi Gourabi B, van Kleef JW, Dahan A: Differential effect of morphine and morphine-6- on the control of breathing in the anesthetized cat. Anesthesiology. 2008 Oct;109(4):689-97. BACKGROUND: Morphine's metabolite, morphine-6- (M6G), activates the mu-opioid receptor. METHODS: Step changes in end-tidal concentration were applied in cats anesthetized with alpha-chloralose-urethane. |
1(0,0,0,1) | Details |