Protein Information

Name albumin
Synonyms ALB; Albumin; PRO0883; PRO0903; PRO1341; PRO1708; PRO2044; PRO2619…

Compound Information

Name sodium fluoride
CAS sodium fluoride (NaF)

Reference List

PubMed Abstract RScore(About this table)
9526672 Kurosaka K, Senba S, Tsubota H, Kondo H: A new enzymatic assay for selectively measuring conjugated bilirubin concentration in serum with use of bilirubin oxidase. Clin Chim Acta. 1998 Jan 30;269(2):125-36.

At pH 5.5 BOD can oxidize only conjugated bilirubin in the presence of reagents such as sodium fluoride and N-acetylcysteine which can decrease BOD reactivity to unconjugated bilirubin and bilirubin covalently bound to albumin (delta bilirubin).
81(1,1,1,1) Details
14621001 Ide K, Hattori M, Yoshinari M, Kawada E, Oda Y: The influence of albumin on corrosion resistance of titanium in fluoride solution. Dent Mater J. 2003 Sep;22(3):359-70.

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12419628 Huang HH: Effect of fluoride and albumin concentration on the corrosion behavior of Ti-6Al-4V alloy. Biomaterials. 2003 Jan;24(2):275-82.

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9164701 Kimm MH, Hardin JA, Gall DG: Transport of albumin into the intestinal lumen of the rat. Can J Physiol Pharmacol. 1997 Mar;75(3):193-8.

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15878783 Huang HH, Lee TH: Electrochemical impedance spectroscopy study of Ti-6Al-4V alloy in artificial saliva with fluoride and/or bovine albumin. Dent Mater. 2005 Aug;21(8):749-55.

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8932512 Pico GA: Thermal stability of human serum albumin by sodium halide salts. Biochem Mol Biol Int. 1996 Feb;38(1):1-6.


It was found that the sodium halides increase the "melting temperature" and the enthalpy of unfolding of albumin in the following order: F- < Cl- < Br- < I-.
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11704544 Wang P, Verin AD, Birukova A, Gilbert-McClain LI, Jacobs K, Garcia JG: Mechanisms of sodium fluoride-induced endothelial cell barrier dysfunction: role of MLC phosphorylation. Am J Physiol Lung Cell Mol Physiol. 2001 Dec;281(6):L1472-83.

NaF, a potent G protein activator and Ser/Thr phosphatase inhibitor, significantly increased albumin permeability and decreased transcellular electrical resistance (TER), indicating endothelial cell (EC) barrier impairment.
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19148585 Kant V, Srivastava AK, Verma PK, Raina R: Alterations in biochemical parameters during subacute toxicity of fluoride alone and in conjunction with aluminum sulfate in goats. Biol Trace Elem Res. 2009 Jul;130(1):20-30. Epub 2009 Jan 17.

In present study, sodium fluoride at 20 mg/kg alone and in conjunction with aluminum sulfate at 150 mg/kg was administered orally daily for 30 days in healthy goats of group 1 and 2, respectively, to access the alterations in the various biochemical parameters during subacute toxicity of fluoride alone and in conjunction with aluminum sulfate.
In Group 1, significant alterations in plasma glucose, blood urea nitrogen (BUN), creatinine, total protein, albumin, globulin, albumin/globulin ratio, magnesium, and sodium were observed on different days of exposure from their pre-exposure values.
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15080879 Ceron JJ, Martinez-Subiela S, Hennemann C, Tecles F: The effects of different anticoagulants on routine canine plasma biochemistry. Vet J. 2004 May;167(3):294-301.

The effects of heparin, ethylenediaminetetraacetic acid (EDTA), sodium citrate and sodium fluoride/potassium oxalate on plasma biochemistry results in dogs were studied and compared with serum.
Differences in albumin, acetylcholinesterase, ionized calcium and potassium were found between serum and heparinized plasma.
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19425189 Kanbur M, Eraslan G, Silici S, Karabacak M: Effects of sodium fluoride exposure on some biochemical parameters in mice: evaluation of the ameliorative effect of royal jelly applications on these parameters. Food Chem Toxicol. 2009 Jun;47(6):1184-9.

Furthermore, serum cholesterol, triglyceride, glucose, total protein and albumin levels, and aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alcaline phosphatase (ALP) activities were evaluated.
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19709569 Kanbur M, Eraslan G, Silici S, Karabacak M: Effects of Sodium Fluoride Exposure on Some Biochemical Parameters in Mice: Evaluation of The Ameliorative Effect of Royal Jelly Applications on These Parameters. Food Chem Toxicol. 2009 Feb 10.

Furthermore, serum cholesterol, triglyceride, glucose, total protein and albumin levels, and aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alcaline phosphatase (ALP) activities were evaluated.
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14709893 Tsutsumi T, Tokumura A, Yamaguchi M, Kitazawa S, Tanigawara Y: Phorbol myristate acetate stimulates degradation of a structural analogue of platelet-activating factor to a neutral lipid in human leukemic K562 cells: relevance to the release of lipids. Biol Pharm Bull. 2004 Jan;27(1):24-8.


Its extracellular release was monitored using an albumin back-extraction method, and its metabolic degradation was analyzed by TLC.
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16226369 Lambot N, Lebrun P, Delporte C, De Vriese C, Delogne-Desnoeck J, Vanbellinghen AM, Graff G, Meuris S: Effect of IPs, cAMP, and cGMP on the hPL and hCG secretion from human term placenta. Mol Cell Endocrinol. 2005 Nov 24;243(1-2):80-5. Epub 2005 Oct 13.


The in vitro release of both hormones can be stimulated by calcium inflow and by albumin.
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