| PubMed |
Abstract |
RScore(About this table) |
| 11535247 |
Thier R, Balkenhol H, Lewalter J, Selinski S, Dommermuth A, Bolt HM: Influence of polymorphisms of the human glutathione transferases and cytochrome P450 2E1 enzyme on the metabolism and toxicity of ethylene oxide and acrylonitrile. Mutat Res. 2001 Oct 1;482(1-2):41-6.
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82(1,1,1,2) |
Details |
| 10463383 |
Thier R, Lewalter J, Kempkes M, Selinski S, Bruning T, Bolt HM: Haemoglobin adducts of acrylonitrile and ethylene oxide in acrylonitrile workers, dependent on polymorphisms of the glutathione transferases GSTT1 and GSTM1. Arch Toxicol. 1999 Jun-Jul;73(4-5):197-202.
|
7(0,0,1,2) |
Details |
| 10919741 |
Fennell TR, MacNeela JP, Morris RW, Watson M, Thompson CL, Bell DA: Hemoglobin adducts from acrylonitrile and ethylene oxide in cigarette smokers: effects of glutathione S-transferase T1-null and M1-null genotypes. Cancer Epidemiol Biomarkers Prev. 2000 Jul;9(7):705-12.
The objectives of this study were to examine the relationship between cigarette smoking and hemoglobin adducts derived from ACN and EO and to investigate whether null genotypes for glutathione transferase (GSTM1 and GSTT1) alter the internal dose of these agents. |
2(0,0,0,2) |
Details |
| 9348438 |
Sumner SC, Selvaraj L, Nauhaus SK, Fennell TR: Urinary metabolites from F344 rats and B6C3F1 mice coadministered acrylamide and acrylonitrile for 1 or 5 days. Chem Res Toxicol. 1997 Oct;10(10):1152-60.
In addition, mice had an increased (p < 0.05) percentage of dose excreted as metabolites derived from GSH conjugation with AM, AN, CEO, or GA after five exposures as compared with one exposure that may be related to a significant increase in the synthesis of GSH or an increase in glutathione transferase activity. |
1(0,0,0,1) |
Details |