Protein Information

Name Glucose dependent insulinotropic polypeptide
Synonyms GIP; Gastric inhibitory polypeptide; Gastric inhibitory polypeptide precursor; Glucose dependent insulinotropic polypeptide; Gastric inhibitory polypeptides; Gastric inhibitory polypeptide precursors; Glucose dependent insulinotropic polypeptides

Compound Information

Name chloralose
CAS

Reference List

PubMed Abstract RScore(About this table)
8946334 Nishizawa M, Nakabayashi H, Uchida K, Nakagawa A, Niijima A: The hepatic vagal nerve is receptive to incretin hormone glucagon-like peptide-1, but not to glucose-dependent insulinotropic polypeptide, in the portal vein. J Auton Nerv Syst. 1996 Nov 6;61(2):149-54.

To examine whether incretin hormones, truncated glucagon-like peptide-1 (tGLP-1) and glucose-dependent insulinotropic polypeptide (GIP), are recognized by the hepatic vagal nerve, changes of the impulse discharge rate in the afferent vagus upon their intraportal administrations were measured in situ in rats anesthetized with urethan and chloralose.
31(0,1,1,1) Details
16608883 Deacon CF, Plamboeck A, Rosenkilde MM, de Heer J, Holst JJ: GIP-(3-42) does not antagonize insulinotropic effects of GIP at physiological concentrations. Am J Physiol Endocrinol Metab. 2006 Sep;291(3):E468-75. Epub 2006 Apr 11.

Glucose-dependent insulinotropic polypeptide [GIP-(1-42)] is degraded by dipeptidyl peptidase IV (DPP IV), forming GIP-(3-42).
The ability of GIP-(3-42) to affect the antihyperglycemic or insulinotropic actions of GIP-(1-42) was examined in chloralose-anesthetized pigs given intravenous glucose.
1(0,0,0,1) Details