Protein Information

Name alkaline phosphatase
Synonyms ALP 1; Alkaline phosphatase; ALPG; ALPPL; ALPPL 2; ALPPL2; GCAP; Germ cell alkaline phosphatase…

Compound Information

Name acrylonitrile
CAS 2-propenenitrile

Reference List

PubMed Abstract RScore(About this table)
516533 Ivanov VV, Grishchenko DA, Klimatskaia LG: [Blood serum enzymes in assessing the nature of the liver lesion and the effectiveness of chemotherapeutic actions in acrylonitrile poisoning]. Vopr Med Khim. 1979 Nov-Dec;25(6):715-8.

After intraperitoneal administration of acrylonitrile into rats, fructose monophosphate aldolase was found in blood serum, activity of butyryl cholinesterase was inhibited but activity of alkaline phosphatase was unaltered in rat blood serum; these data demonstrate the necro-bystrophic type impairment.
81(1,1,1,1) Details
8559492 Ferreira A, Urena P, Ang KS, Simon P, Morieux C, Souberbielle JC, de Vernejoul MC, Drueke TB: Relationship between serum beta 2-microglobulin, bone histology, and dialysis membranes in uraemic patients. Nephrol Dial Transplant. 1995;10(9):1701-7.


In contrast, serum beta 2M levels were higher in patients on C than on SHF membrane: 59.8 +/- 14.1 versus 32.8 +/- 8.7 mg/l, and so were serum total alkaline phosphatase and osteocalcin levels: 323 +/- 167 versus 173 +/- 50 IU/l, and 656 +/- 395 versus 288 +/- 263 ng/ml respectively.
2(0,0,0,2) Details
11390725 Ferreira A, Ghazali A, Galvao J, Souberbielle JC, Jehle PM, Mohan S, Descamps-Latscha B, Oprisiu R, Fournier A, Drueke TB: Effect of type of dialysis membrane on bone in haemodialysis patients. Nephrol Dial Transplant. 2001 Jun;16(6):1230-8.


Similarly, plasma bone-specific alkaline phosphatase and osteocalcin (markers of bone formation), and cross-laps (marker of bone resorption) remained unchanged.
1(0,0,0,1) Details
1964927 Grigor'eva IK: [Study of the activity of membrane-bound leukocyte enzymes in chronic acrylonitrile poisoning in experimental studies and occupational environment]. Gig Tr Prof Zabol. 1990;(11):28-31.

Deviations were found in the activity of the marker enzymes of alkaline phosphatase neutrophil secretory granules and myeloperoxidase.
1(0,0,0,1) Details