PubMed |
Abstract |
RScore(About this table) |
17080406 |
Chantara W, Watcharasit P, Thiantanawat A, Satayavivad J: Acrylonitrile-induced extracellular signal-regulated kinase (ERK) activation via protein kinase C (PKC) in SK-N-SH neuroblastoma cells. J Appl Toxicol. 2006 Nov-Dec;26(6):517-23.
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81(1,1,1,1) |
Details |
2783141 |
Bignon E, Ogita K, Kishimoto A, Gilbert J, Abecassis J, Miquel JF, Nishizuka Y: Modes of inhibition of protein kinase C by triphenylacrylonitrile antiestrogens. Biochem Biophys Res Commun. 1989 Sep 29;163(3):1377-83.
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4(0,0,0,4) |
Details |
2226814 |
Bignon E, Pons M, Gilbert J, Nishizuka Y: Multiple mechanisms of protein kinase C inhibition by triphenylacrylonitrile antiestrogens. FEBS Lett. 1990 Oct 1;271(1-2):54-8.
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2(0,0,0,2) |
Details |
8749684 |
Carracedo J, Ramirez R, Pintado O, Gomez-Villamandos JC, Martin-Malo A, Rodriguez M, Aljama P: Cell aggregation and apoptosis induced by hemodialysis membranes. . J Am Soc Nephrol. 1995 Dec;6(6):1586-91.
Louis, MO) a protein kinase C (PKC)-inhibitor, suggesting that cell apoptosis induced by the CU membrane is mediated by a PKC-dependent cell activation. |
1(0,0,0,1) |
Details |
1738150 |
Dore JC, Gilbert J, Bignon E, Crastes de Paulet A, Ojasoo T, Pons M, Raynaud JP, Miquel JF: Multivariate analysis by the minimum spanning tree method of the structural determinants of diphenylethylenes and triphenylacrylonitriles implicated in estrogen receptor binding, protein kinase C activity, and MCF7 cell proliferation. J Med Chem. 1992 Feb 7;35(3):573-83.
The responses measured were (a) relative binding affinity (RBA) for the cytosol estrogen receptor (ER), (b) ability to promote the growth of the human MCF7 breast cancer cell-line, (c) cytotoxicity in MCF7 cells, and (d) ability to stimulate or inhibit protein kinase C (PKC) III activity under three different conditions of enzyme activation. |
1(0,0,0,1) |
Details |