| Name | carbonic anhydrase |
|---|---|
| Synonyms | CA IX; CA1; Carbonic anhydrase I; CA2; CAII; Carbonic anhydrase II; Carbonic dehydratase; Carbonic anhydrase III… |
| Name | carbon disulfide |
|---|---|
| CAS | carbon disulfide |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15792633 | Haritos VS, Dojchinov G: Carbonic anhydrase metabolism is a key factor in the toxicity of CO2 and COS but not CS2 toward the flour beetle Tribolium castaneum [Coleoptera: Tenebrionidae]. Comp Biochem Physiol C Toxicol Pharmacol. 2005 Jan;140(1):139-47. The analogues (CO (2)), carbonyl sulfide (COS) and carbon disulfide (CS (2)) have been useful as substrate probes for enzyme activities. Here we explored the affinity of the enzyme carbonic anhydrase for its natural substrate CO (2), as well as COS and CS (2) (1) by in vitro kinetic metabolism studies using pure enzyme and (2) through mortality bioassay of insects exposed to toxic levels of each of the gases during carbonic anhydrase inhibition. |
3(0,0,0,3) | Details |
| 18341261 | Almajan GL, Barbuceanu SF, Innocenti A, Scozzafava A, Supuran CT: Carbonic anhydrase inhibitors. J Enzyme Inhib Med Chem. 2008 Feb;23(1):101-7. Novel mercapto-1,3,4-oxadiazole and -1,2,4-triazole derivatives were synthesized by various pathways starting from 4-(4-halogeno-phenylsulfonyl) hydrazides which were reacted with carbon disulfide or isothiocyanates. |
3(0,0,0,3) | Details |
| 17059166 | Zareef M, Innocenti A, Iqbal R, Zaidi JH, Arfan M, Scozzafava A, Supuran CT: Carbonic anhydrase inhibitors. J Enzyme Inhib Med Chem. 2006 Aug;21(4):351-9. A series of chiral 1,3,4-oxadiazole-5-thiols incorporating 2-substituted-benzenesulfonamide moieties has been prepared from amino acids, via the ester and carbohydrazide intermediate, followed by cyclization with carbon disulfide. |
3(0,0,0,3) | Details |
| 11259012 | Sinnecker S, Brauer M, Koch W, Anders E: Cs (2) fixation by carbonic anhydrase model systems-a new substrate in the catalytic cycle. Inorg Chem. 2001 Feb 26;40(5):1006-13. |
2(0,0,0,2) | Details |
| 4971738 | Pocker Y, Stone JT: The catalytic versatility of erythrocyte carbonic anhydrase. Biochemistry. 1968 Sep;7(9):3021-31. |
1(0,0,0,1) | Details |
| 3814176 | Chengelis CP, Neal RA: Oxidative metabolism of carbon disulfide by isolated rat hepatocytes and microsomes. Biochem Pharmacol. 1987 Feb 1;36(3):363-8. |
0(0,0,0,0) | Details |