| Name | NK 1 receptor |
|---|---|
| Synonyms | NK 1 receptor; NK 1R; NK1R; NKIR; Neurokinin 1 receptor; SPR; Substance P Receptor; TAC1R… |
| Name | chloralose |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9502263 | Radhakrishnan V, Iyengar S, Henry JL: The nonpeptide NK-1 receptor antagonists LY303870 and LY306740 block the responses of spinal dorsal horn neurons to substance P and to peripheral noxious stimuli. Neuroscience. 1998 Apr;83(4):1251-60. Extracellular recordings were obtained using multi-barrel electrodes from L4-L7 segments of the spinal cord in cats anaesthetized with alpha-chloralose and spinalized at the L1 level. |
2(0,0,0,2) | Details |
| 9724281 | Wilson LB, Hand GA: Segmental effect of spinal NK-1 receptor blockade on the pressor reflex. Am J Physiol. 1998 Sep;275(3 Pt 2):H789-96. Cats were anesthetized with alpha-chloralose and urethan, and a laminectomy was performed. |
1(0,0,0,1) | Details |
| 9383221 | Radhakrishnan V, Henry JL: Electrophysiological evidence that neurokinin A acts via NK-1 receptors in the cat dorsal horn. Eur J Neurosci. 1997 Sep;9(9):1977-85. The aim of the present study was to investigate the effects of the non-peptide NK-2 receptor antagonist, SR 48968 on the responses of dorsal horn neurons to iontophoretic application of the endogenous NK-2 receptor ligand, neurokinin A, and on synaptically elicited responses in chloralose-anaesthetized cats. |
0(0,0,0,0) | Details |
| 7538641 | Radhakrishnan V, Henry JL: Antagonism of nociceptive responses of cat spinal dorsal horn neurons in vivo by the NK-1 receptor antagonists CP-96,345 and CP-99,994, but not by CP-96,344. Neuroscience. 1995 Feb;64(4):943-58. Extracellular and intracellular studies were undertaken to test the effects of the non-peptide, substance P (NK-1) receptor antagonists CP-96,345 and CP-99,994, and of CP-96,344, the inactive enantiomer of CP-96,345, on the responses of spinal dorsal horn neurons to peripheral noxious and non-noxious cutaneous stimuli in spinalized cats anesthetized with alpha-chloralose. |
32(0,1,1,2) | Details |