16626973 |
Stefanovic B, Bosetti F, Silva AC: Modulatory role of cyclooxygenase-2 in cerebrovascular coupling. Neuroimage. 2006 Aug 1;32(1):23-32. Epub 2006 Apr 19.
To investigate the role of cyclooxygenase-2 (COX-2) in the cerebrovascular coupling, hemodynamic and neuronal responses to forepaw stimulation were measured in alpha-chloralose-anesthetized rats (N = 18) before and after intravenous administration of Meloxicam (MEL), a preferential COX-2 inhibitor, and following a bolus of prostaglandin E (2) (PGE (2)), a prominent vasodilatatory product of COX-2 catalyzed metabolism of arachidonic acid. |
32(0,1,1,2) |
Details |