| Name | 5 HT 1B |
|---|---|
| Synonyms | 5 HT 1B; S12; 5 HT 1D beta; 5 HT1B; 5 HT1DB; 5 hydroxytryptamine (serotonin) receptor 1B; 5 hydroxytryptamine 1B receptor; HTR1B… |
| Name | chloralose |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9680249 | Bootle DJ, Adcock JJ, Ramage AG: The role of central receptors in the bronchoconstriction evoked by inhaled in anaesthetised guinea-pigs. Neuropharmacology. 1998;37(2):243-50. The effects of intracisternal (i.c) injections of the 5-HT1A receptor agonists, and 8-OH-DPAT, and the antagonists WAY-100635; and (-)-pindolol, the 5-HT1B/1D receptor agonist and antagonist GR127935, the 5-HT2 receptor agonist DOI and the antagonist cinanserin, the 5-HT3 receptor antagonist granisetron, the alpha-adrenoceptor agonist clonidine and the antagonist idazoxan, the D2 receptor antagonists (-)-sulpiride and the uptake inhibitor fluoxetine on -evoked increase in tracheal inflation pressure (bronchoconstriction) were investigated in alpha-chloralose anaesthetised, neuromuscularly blocked, artificially ventilated guinea-pigs. |
32(0,1,1,2) | Details |
| 8032949 | Kishimoto T, Yamanaka T, Amano T, Todo N, Sasa M: 5-HT1A receptor-mediated inhibition of lateral vestibular nucleus neurons projecting to the abducens nucleus. Brain Res. 1994 Apr 25;644(1):47-51. Electrophysiological studies were performed using cats anesthetized with alpha-chloralose, to elucidate the receptor subtypes involved in the -induced inhibition of the lateral vestibular nucleus (LVN) neurons projecting to or through the abducens nucleus. Microiontophoretically applied 1-(3-chlorophenyl) piperazine (mCPP), a 5-HT1B agonist inhibited the orthodromic spike elicited by vestibular nerve stimulation and -induced firing in only a small number of the LVN neurons. 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), a 5-HT2 agonist, rarely affected these neurons. |
1(0,0,0,1) | Details |
| 14614913 | Goadsby PJ, Classey JD: Evidence for (5-HT) 1B, 5-HT1D and 5-HT1F receptor inhibitory effects on trigeminal neurons with craniovascular input. Neuroscience. 2003;122(2):491-8. The superior sagittal sinus (SSS) was isolated in alpha-chloralose (60 mg/kg, i.p. and 20 mg/kg i.v.i. supplementary 2 hourly) anaesthetised cats. |
8(0,0,0,8) | Details |
| 9384509 | Goadsby PJ, Knight Y: Inhibition of trigeminal neurones after intravenous administration of naratriptan through an action at (5-HT (1B/1D)) receptors. Br J Pharmacol. 1997 Nov;122(5):918-22. Cats were anaesthetized with alpha-chloralose (60 mg kg (-1), intraperitoneal), paralyzed (gallamine 6 mg kg (-1), intravenously) and ventilated. |
4(0,0,0,4) | Details |
| 12384251 | Lambert GA, Boers PM, Hoskin KL, Donaldson C, Zagami AS: Suppression by eletriptan of the activation of trigeminovascular sensory neurons by glyceryl trinitrate. Brain Res. 2002 Oct 25;953(1-2):181-8. Cats were anaesthetised with alpha-chloralose, immobilised and artificially ventilated. Iontophoretic application of the 5-HT (1B/1D) receptor agonist eletriptan (50 nA) at the peak of the response decreased the discharge rate of neurons towards pre-GTN control levels. |
3(0,0,0,3) | Details |
| 14725972 | Hoskin KL, Lambert GA, Donaldson C, Zagami AS: The 5-hydroxytryptamine1B/1D/1F receptor agonists eletriptan and naratriptan inhibit trigeminovascular input to the nucleus tractus solitarius in the cat. Brain Res. 2004 Feb 13;998(1):91-9. Chloralose-anaesthetised cats (n=16) were prepared for single neuron recording. This suppression could be antagonized by the concurrent ejection (20-50 nA) of the 5-HT (1B/1D) receptor antagonist GR127935. |
2(0,0,0,2) | Details |
| 15152026 | Gu B, Olejar KJ, Reiter JP, Thor KB, Dolber PC: Inhibition of bladder activity by 5-hydroxytryptamine1 serotonin receptor agonists in cats with chronic spinal cord injury. J Pharmacol Exp Ther. 2004 Sep;310(3):1266-72. Epub 2004 May 19. We also investigated GR-46611 (3-[3-(2-dimethylaminoethyl)-1H-indol-5-yl]-N-(4-methoxybenzyl) acrylamide) , which has agonist activity predominantly at 5-HT1B and 5-HT1D receptors but also at the 5-HT1A receptor. Chloralose-anesthetized cats were catheterized through the bladder dome for saline-filling cystometry. |
2(0,0,0,2) | Details |
| 16549369 | Stark JA, Davies KE, Williams SR, Luckman SM: Functional magnetic resonance imaging and c-Fos mapping in rats following an anorectic dose of m-chlorophenylpiperazine. Neuroimage. 2006 Jul 1;31(3):1228-37. Epub 2006 Mar 20. An anorectic dose of the 5-HT (1B/2C) receptor agonist m-chlorophenylpiperazine (mCPP; 3 mg/kg s.c.) was used to compare BOLD contrast fMRI with expression of the c-Fos protein. mCPP was administered to rats, which were then anaesthetised and perfused with fixative 90 min later to allow immunohistochemistry. In a separate experiment, rats were imaged using a T (2)*-weighted gradient echo in a 7 T magnet for 70 min under alpha-chloralose anaesthesia. |
1(0,0,0,1) | Details |
| 15197536 | Lambert GA, Donaldson C, Hoskin KL, Boers PM, Zagami AS: Dilatation induced by in the middle meningeal artery of the anaesthetised cat. Naunyn Schmiedebergs Arch Pharmacol. 2004 Jun;369(6):591-601. Epub 2004 May 7. In chloralose-anaesthetised cats, we studied the effects of intravenous and intra-carotid injections of on the middle meningeal artery and the way these were modified by antagonists. |
0(0,0,0,0) | Details |
| 7537469 | Nobrega AC, Meintjes AF, Ally A, Wilson LB: Modulation of reflex pressor response to contraction and effect on substance P release by spinal 5-HT1A receptors. Am J Physiol. 1995 Apr;268(4 Pt 2):H1577-85. Static contractions of the triceps surae muscle of chloralose-anesthetized cats were induced by stimulating the cut L7 and S1 ventral roots. |
0(0,0,0,0) | Details |