| Name | protein kinase C (protein family or complex) |
|---|---|
| Synonyms | Protein kinase C; PKC |
| Name | chloralose |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 15579573 | MacGowan GA, Rager J, Shroff SG, Mathier MA: In vivo alpha-adrenergic responses and troponin I phosphorylation: anesthesia interactions. J Appl Physiol. 2005 Apr;98(4):1163-70. Epub 2004 Dec 3. We hypothesized that alpha-adrenergic-mediated contractile dysfunction is mediated through protein kinase C phosphorylation of troponin I, which in in vitro experiments has been shown to reduce actomyosin Mg-ATPase activity. As anesthesia agents can produce markedly different effects on contractility, we studied two agents: avertin and alpha-chloralose-urethane. |
2(0,0,0,2) | Details |
| 12131099 | Zaugg M, Lucchinetti E, Spahn DR, Pasch T, Garcia C, Schaub MC: Differential effects of anesthetics on mitochondrial K (ATP) channel activity and cardiomyocyte protection. Anesthesiology. 2002 Jul;97(1):15-23. Conversely, urethane, 2,2,2-trichloroethanol (main metabolite of alpha-chloralose and chloral hydrate), and the opioid potentiated the channel-opening effect of diazoxide, which was abrogated by coadministration of chelerythrine, a specific protein kinase C inhibitor. |
31(0,1,1,1) | Details |
| 8384119 | Schepelmann K, Messlinger K, Schmidt RF: The effects of phorbol ester on slowly conducting afferents of the cat's knee joint. Exp Brain Res. 1993;92(3):391-8. The effects of beta-phorbol 12,13-dibutyrate (PDBu) on the discharge properties of slowly conducting knee joint afferents (group III and group IV fibers) were studied to determine the role of protein kinase C in nociception. Extracellular single unit recordings were made from small filaments dissected from the medial articular nerve in cats anesthetized with alpha-chloralose. |
3(0,0,0,3) | Details |