| Name | tissue transglutaminase |
|---|---|
| Synonyms | Protein glutamine gamma glutamyltransferase 2; TG(C); TG2; TGC; TGM 2; TGM2; TGM2 protein; TGase C… |
| Name | carbon tetrachloride |
|---|---|
| CAS | tetrachloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 17708605 | Qiu JF, Zhang ZQ, Chen W, Wu ZY: Cystamine ameliorates liver fibrosis induced by carbon tetrachloride via inhibition of tissue transglutaminase. World J Gastroenterol. 2007 Aug 28;13(32):4328-32. |
82(1,1,1,2) | Details |
| 20004152 | D'Argenio G, Amoruso DC, Mazzone G, Vitaglione P, Romano A, Ribecco MT, D'Armiento MR, Mezza E, Morisco F, Fogliano V, Caporaso N: Garlic extract prevents CCl (4)-induced liver fibrosis in rats: The role of tissue transglutaminase. Dig Liver Dis. 2009 Dec 7. METHODS: Rat liver fibrosis was induced by intraperitoneal injection of carbon tetrachloride (CCl (4)) for 7 weeks. |
7(0,0,0,7) | Details |
| 15188175 | Issa R, Zhou X, Constandinou CM, Fallowfield J, Millward-Sadler H, Gaca MD, Sands E, Suliman I, Trim N, Knorr A, Arthur MJ, Benyon RC, Iredale JP: Spontaneous recovery from micronodular cirrhosis: evidence for incomplete resolution associated with matrix cross-linking. Gastroenterology. 2004 Jun;126(7):1795-808. Livers were analyzed for evidence of matrix degradation, matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) expression, stellate cell apoptosis, tissue transglutaminase (tTg) expression, and matrix cross-linking during spontaneous recovery of up to 366 days. |
1(0,0,0,1) | Details |
| 19099152 | Dias JV, Paredes BD, Mesquita LF, Carvalho AB, Kozlowski EO, Lessa AS, Takiya CM, Resende CM, Coelho HS, Campos-de-Carvalho AC, Rezende GF, Goldenberg RC: An ultrasound and histomorphological analysis of experimental liver cirrhosis in rats. Braz J Med Biol Res. 2008 Nov;41(11):992-9. We investigated whether liver injury by dual exposure to and carbon tetrachloride (EtOH + CCl4) for 15 weeks would persist after hepatotoxic agents were removed (EtOH + CCl4/8wR). Tissue transglutaminase increased in both groups (EtOH + CCl4: 66.4 +/- 8%, P < 0.01; EtOH + CCl4/8wR: 58.8 +/- 21%, P < 0.01) vs control (7.9 +/- 0.8%). |
1(0,0,0,1) | Details |
| 17060319 | Zhou X, Jamil A, Nash A, Chan J, Trim N, Iredale JP, Benyon RC: Impaired proteolysis of collagen I inhibits proliferation of hepatic stellate cells: implications for regulation of liver fibrosis. J Biol Chem. 2006 Dec 29;281(52):39757-65. Epub 2006 Oct 23. Collagen I was shown to be rendered resistant to matrix metalloproteinases by artificial cross-linking in vitro using tissue transglutaminase exerted similar antiproliferative effects on stellate cells to r/r collagen. |
1(0,0,0,1) | Details |
| 19069636 | Quintanilha LF, Mannheimer EG, Carvalho AB, Paredes BD, Dias JV, Almeida AS, Gutfilen B, Barbosa da Fonseca LM, Resende CM, Rezende GF, Campos de Carvalho AC, Goldenberg RC: Bone marrow cell transplant does not prevent or reverse murine liver cirrhosis. Cell Transplant. 2008;17(8):943-53. Female Wistar rats were fed a liquid diet and received intraperitoneal injections of carbon tetrachloride (CCl4) over 15 weeks. Indirect immunofluorescence was performed to detect the amount of tissue transglutaminase 2. |
1(0,0,0,1) | Details |