| Name | glutamate receptor |
|---|---|
| Synonyms | GRINL1A; GUP1; GUP2; GRINL1A combined protein; GRINL1A combined protein Gcom10; GRINL1A combined protein Gcom10 precursor; GRINL1A combined protein Gcom11; GRINL1A combined protein Gcom11 precursor… |
| Name | chloralose |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16733059 | Cao WH, Morrison SF: Glutamate receptors in the raphe pallidus mediate brown adipose tissue thermogenesis evoked by activation of dorsomedial hypothalamic neurons. Neuropharmacology. 2006 Sep;51(3):426-37. Epub 2006 May 30. We determined the role of glutamate receptor activation in the rostral raphe pallidus (RPa) in mediating the sympathoexcitatory responses in HR, BAT SNA and RSNA following disinhibition of DMH neurons in urethane/chloralose anesthetized, artificially ventilated rats. |
32(0,1,1,2) | Details |
| 14514030 | Morrison SF: transmission in the rostral ventrolateral medullary sympathetic premotor pathway. Cell Mol Neurobiol. 2003 Oct;23(4-5):761-72. Iontophoretic and pressure ejection of glutamate receptor agonists and antagonists was made onto antidromically identified splanchnic and SPNs before and during electrical stimulation of the RVLM in urethane/chloralose-anesthetized, artificially ventilated rats. 3. |
32(0,1,1,2) | Details |
| 9815076 | Liu Z, Chen CY, Bonham AC: Metabotropic glutamate receptors depress vagal and aortic baroreceptor signal transmission in the NTS. Am J Physiol. 1998 Nov;275(5 Pt 2):H1682-94. In alpha-chloralose-anesthetized rabbits, we determined the number of extracellular action potentials synaptically evoked by low (1 Hz)- or high-frequency vagal (3-20 Hz) or aortic depressor nerve (ADN) (6-80 Hz) stimulation and postsynaptically evoked by the ionotropic glutamate receptor agonist alpha-amino-3--5-methylisoxazole-4- (AMPA). |
32(0,1,1,2) | Details |
| 8421957 | McCulloch J, Ozyurt E, Park CK, Nehls DG, Teasdale GM, Graham DI: Glutamate receptor antagonists in experimental focal cerebral ischaemia. . Acta Neurochir Suppl. 1993;57:73-9. In chloralose-anaesthetised cats, focal cerebral ischaemia was produced by permanent occlusion of one middle cerebral artery (MCA) and the animal sacrificed 6 hours later. |
2(0,0,0,2) | Details |
| 16125857 | Cerri M, Morrison SF: Activation of lateral hypothalamic neurons stimulates brown adipose tissue thermogenesis. Neuroscience. 2005;135(2):627-38. To determine if activation of lateral hypothalamic area neurons influences sympathetically-regulated thermogenesis in brown adipose tissue, we microinjected bicuculline (120 pmol, 60 nl, unilateral) into the lateral hypothalamic area in urethane/chloralose-anesthetized, artificially-ventilated rats. Subsequent microinjections of (30 nmol, 60 nl) to inhibit local neurons in raphe pallidus or in dorsomedial hypothalamus or of glutamate receptor antagonists into dorsomedial hypothalamus promptly reversed the increases in brown adipose tissue sympathetic nerve activity, brown adipose tissue temperature and heart rate evoked by disinhibition of neurons in lateral hypothalamic area. |
1(0,0,0,1) | Details |
| 9479671 | Haxhiu MA, Erokwu B, Dreshaj IA: The role of excitatory amino acids in airway reflex responses in anesthetized dogs. J Auton Nerv Syst. 1997 Dec 11;67(3):192-9. Experiments were performed in chloralose anesthetized, paralyzed and mechanically ventilated beagle dogs (n = 18), under hyperoxic, normocapnic, and normohydric conditions. However, topical application or microinjection of AMPA/kainate subtype of glutamate receptor selective antagonists markedly reduced reflex increase in tracheal tone induced by (1) lung deflation, (2) stimulation of laryngeal cold receptors, and (3) activation of peripheral or central chemoreceptors. |
1(0,0,0,1) | Details |
| 9843813 | Scislo TJ, O'Leary DS: Differential control of renal vs. sympathetic nerve activity by NTS A2a and P2x purinoceptors. Am J Physiol. 1998 Dec;275(6 Pt 2):H2130-9. We conclude that NTS A2a-purinoceptor activation evokes differential sympathetic responses similar to those observed during hemorrhage, whereas P2x-purinoceptor and glutamate-receptor activation evokes differential inhibition of sympathetic outputs similar to arterial baroreflex responses. RSNA was recorded simultaneously with pre-ASNA or post-ASNA in chloralose-urethan-anesthetized male Sprague-Dawley rats. |
1(0,0,0,1) | Details |
| 7598871 | Yamanaka T, Amano T, Sasa M, Matsunaga T: Prednisolone excitation of medial vestibular nucleus neurons in cats. Eur Arch Otorhinolaryngol. 1995;252(2):112-8. An electrophysiological study was performed to determine whether prednisolone hydrochloride directly influenced neuronal activities of the medial vestibular nucleus (MVN) in alpha-chloralose-anesthetized cats. Microiontophoretic GDEE, a non-selective glutamate receptor antagonist, inhibited - and rotation-induced neuronal discharges without affecting prednisolone-induced increases in neuronal responses of MVN. |
1(0,0,0,1) | Details |
| 16580142 | Cerri M, Morrison SF: Corticotropin releasing factor increases in brown adipose tissue thermogenesis and heart rate through dorsomedial hypothalamus and medullary raphe pallidus. Neuroscience. 2006 Jun 30;140(2):711-21. Epub 2006 Mar 31. To identify potential central pathways through which hypothalamic corticotropin releasing factor influences brown adipose tissue thermogenesis, corticotropin releasing factor was microinjected into the lateral ventricle (i.c.v.) or into hypothalamic sites while recording sympathetic outflow to brown adipose tissue, brown adipose tissue temperature, expired CO2, heart rate and arterial pressure in urethane/chloralose-anesthetized, artificially-ventilated rats. These sympathetic responses to i.c.v. corticotropin releasing factor were eliminated by inhibition of neuronal activity in the dorsomedial hypothalamus or in the raphe pallidus, a putative site of sympathetic premotor neurons for brown adipose tissue, and were markedly reduced by microinjection of ionotropic glutamate receptor antagonists into the dorsomedial hypothalamus. |
1(0,0,0,1) | Details |
| 7911523 | Yamanaka T: [Excitatory effects of glucocorticoids on neuronal activity in the medial vestibular nucleus--mediation by glucocorticoid receptor on the membrane]. Nippon Jibiinkoka Gakkai Kaiho. 1994 May;97(5):855-67. The present study was performed to examine the effects of a glucocorticoid, dexamethasone, on neuronal activity in the medial vestibular nucleus (MVN) to determine whether or not the drug acts directly on the MVN neuron using alpha-chloralose-anesthetized cats which were fixed in a stereotaxic instrument placed on a turn-table. Each pipette was filled with dexamethasone (0.1 M), monosodium (1 M), glutamic acid diethylester (GDEE) (0.05 M: a non-selective glutamate receptor antagonist), CoCl2, (0.1 M: a non-specific calcium channel blocker), RU38486 (0.01 M: glucocorticoid receptor antagonist) or canrenoate (0.1 M: a mineralo-cortical receptor antagonist). |
1(0,0,0,1) | Details |
| 12194013 | Bongianni F, Mutolo D, Carfi M, Pantaleo T: Respiratory responses to ionotropic glutamate receptor antagonists in the ventral respiratory group of the rabbit. Pflugers Arch. 2002 Aug;444(5):602-9. Epub 2002 Jun 19. Selective excitatory amino acid receptor antagonists acting on either or non-NMDA receptors were microinjected (30-50 nl) bilaterally into different subregions of the ventral respiratory group (VRG) of alpha-chloralose-urethane anaesthetized, vagotomized, paralysed and artificially ventilated rabbits. |
1(0,0,0,1) | Details |
| 7713805 | Nattie EE, Li A: Rat retrotrapezoid nucleus iono- and metabotropic glutamate receptors and the control of breathing. J Appl Physiol. 1995 Jan;78(1):153-63. We injected 10 nl (unilateral) of glutamate receptor antagonists or agonists into the region of the retrotrapezoid nucleus and measured the phrenic nerve and blood pressure responses. The rats were chloralose-urethan anesthetized, paralyzed, vagotomized, and ventilated, and each injection location was verified anatomically. |
1(0,0,0,1) | Details |
| 12044639 | Peng YJ, Wang N, Gong QL, Li P: Caudal ventrolateral medulla mediates the depressor response elicited by the greater splanchnic nerve afferent stimulation in rats. Neurosci Lett. 2002 Jun 7;325(2):134-8. In the present study, the possible involvement of the CVLM in mediating the depressor response elicited by the greater splanchnic nerve (GSPL) afferent stimulation was explored in rats anesthetized with urethane and alpha-chloralose. Microinjection of lidocaine, and the glutamate receptor antagonists, and 2-amino-7-phosphonolieptanoic acid, into the CVLM significantly blocked the depressor response induced by the GSPL afferent stimulation. |
1(0,0,0,1) | Details |
| 11695702 | Furukawa N, Hatano M, Fukuda H: Glutaminergic vagal afferents may mediate both retching and gastric adaptive relaxation in dogs. Auton Neurosci. 2001 Oct 8;93(1-2):21-30. Ketamine and thiopental- or chloralose-anesthetized dogs were decerebrated, and the dorsal surface of the medulla was exposed. In the second series, effects of glutamate receptor antagonists on gastric corpus responses to esophageal or gastric antral distension were observed. |
1(0,0,0,1) | Details |
| 20065145 | Bardgett ME, McCarthy JJ, Stocker SD: Glutamatergic receptor activation in the rostral ventrolateral medulla mediates the sympathoexcitatory response to hyperinsulinemia. Hypertension. 2010 Feb;55(2):284-90. Epub 2010 Jan 11. Hyperinsulinemic-euglycemic clamps were performed in alpha-chloralose anesthetized, male Sprague-Dawley rats by infusion of insulin (3.75 mU/kg per minute, IV) and 50% solution for 120 minutes. Microinjection of the ionotropic glutamate receptor antagonist into the RVLM significantly reduced lumbar SNA and ABP. |
1(0,0,0,1) | Details |
| 15525805 | Solomon IC: neurotransmission is not required for, but may modulate, hypoxic sensitivity of pre-Botzinger complex in vivo. J Neurophysiol. 2005 Mar;93(3):1278-84. Epub 2004 Nov 3. To test this possibility, the effects of focal pre-BotC hypoxia [induced by (NaCN)] were examined before and after blockade of ionotropic EAA receptors [using (KYN)] in this region in chloralose-anesthetized, vagotomized, mechanically ventilated cats. |
0(0,0,0,0) | Details |