| Name | superoxide dismutase 1 |
|---|---|
| Synonyms | ALS; ALS 1; ALS1; IPOA; Indophenoloxidase A; SOD; SOD 1; SOD1… |
| Name | carbon tetrachloride |
|---|---|
| CAS | tetrachloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19765104 | Smyth R, Munday MR, York MJ, Clarke CJ, Dare T, Turton JA: Dose response and time course studies on superoxide dismutase as a urinary biomarker of carbon tetrachloride-induced hepatic injury in the Hanover Wistar rat. Int J Exp Pathol. 2009 Oct;90(5):500-11. Previous studies have shown that the enzyme /zinc superoxide dismutase (SOD-1) is increased in the urine of rats with carbon tetrachloride (CCl (4))-induced hepatotoxicity. |
6(0,0,1,1) | Details |
| 18306454 | Lee SH, Heo SI, Li L, Lee MJ, Wang MH: Antioxidant and hepatoprotective activities of Cirsium setidens Nakai against CCl4-induced liver damage. Am J Chin Med. 2008;36(1):107-14. The n-BuOH fraction reduced CCl (4)-induced liver injury in rats, and transcript levels of genes encoding antioxidant enzymes such as glutathione peroxidase 1 (GPO1), glutathione peroxidase 3 (GPO3) and superoxide dismutase (SOD1) were elevated in the livers of rats treated with this fraction (500 mg/kg). |
1(0,0,0,1) | Details |
| 18586068 | Smyth R, Turton JA, Clarke CJ, York MJ, Dare TO, Lane CS, Munday MR: Identification of superoxide dismutase as a potential urinary marker of carbon tetrachloride-induced hepatic toxicity. Food Chem Toxicol. 2008 Sep;46(9):2972-83. Epub 2008 Jun 11. The protein was identified by in-gel digestion and nano-electrospray (nano-ES)-tandem mass spectrometry as Cu/Zn superoxide dismutase (SOD-1). |
1(0,0,0,1) | Details |
| 19702266 | Hsu JD, Kao SH, Tu CC, Li YJ, Wang CJ: Solanum nigrum L. extract inhibits 2-acetylaminofluorene-induced hepatocarcinogenesis through overexpression of glutathione S-transferase and antioxidant enzymes. J Agric Food Chem. 2009 Sep 23;57(18):8628-34. Our previous study has found that SN water extract (SNWE) alleviated carbon tetrachloride-induced liver damage in rats. Further investigation revealed that a SNWE supplement increased the expression of glutathione S-transferase-alpha and -mu, the level of transcription factor for protection from oxidative stress, Nrf2, and the level of downstream targets regulated by Nrf2, including peroxidase, superoxide dismutase-1, and catalase. |
1(0,0,0,1) | Details |
| 18036097 | Venugopal SK, Wu J, Catana AM, Eisenbud L, He SQ, Duan YY, Follenzi A, Zern MA: Lentivirus-mediated dismutase1 gene delivery protects against oxidative stress-induced liver injury in mice. Liver Int. 2007 Dec;27(10):1311-22. METHODS: In vitro SOD1 efficacy was tested against two ROS-generating systems: /xanthine oxidase (HX/XO) and hydroxyethyl radicals (HER), whereas in vivo SOD1 efficacy was evaluated in carbon tetrachloride (CCl4)-induced liver injury in C57BL/6 mice. |
10(0,0,1,5) | Details |