Name | ADAMTS 13 |
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Synonyms | A disintegrin and metalloproteinase with thrombospondin motifs 13; TTP; ADAM TS 13; ADAM TS13; ADAMTS 13; ADAMTS 13 precursor; ADAMTS13; UNQ6102/PRO20085… |
Name | carbon tetrachloride |
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CAS | tetrachloromethane |
PubMed | Abstract | RScore(About this table) | |
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17383642 | Kume Y, Ikeda H, Inoue M, Tejima K, Tomiya T, Nishikawa T, Watanabe N, Ichikawa T, Kaneko M, Okubo S, Yokota H, Omata M, Fujiwara K, Yatomi Y: Hepatic stellate cell damage may lead to decreased plasma ADAMTS13 activity in rats. FEBS Lett. 2007 Apr 17;581(8):1631-4. Epub 2007 Mar 20. Plasma ADAMTS13 activity was markedly reduced in dimethylnitrosamine-treated rats, where HSC apoptosis is an essential event, but not in carbon tetrachloride- or thioacetamide-treated rats without HSC apoptosis. |
4(0,0,0,4) | Details |
18042797 | Miyata E, Masuya M, Yoshida S, Nakamura S, Kato K, Sugimoto Y, Shibasaki T, Yamamura K, Ohishi K, Nishii K, Ishikawa F, Shiku H, Katayama N: Hematopoietic origin of hepatic stellate cells in the adult liver. . Blood. 2008 Feb 15;111(4):2427-35. Epub 2007 Nov 27. To test this hypothesis, we generated chimeric mice by transplantation of clonal populations of cells derived from single enhanced green fluorescent protein (EGFP)-marked Lin (-) Sca-1 (+) c-kit (+) CD34 (-) cells and examined the histology of liver tissues obtained from the chimeric mice with carbon tetrachloride (CCl (4))-induced injury. |
0(0,0,0,0) | Details |
16689760 | Niiya M, Uemura M, Zheng XW, Pollak ES, Dockal M, Scheiflinger F, Wells RG, Zheng XL: Increased ADAMTS-13 proteolytic activity in rat hepatic stellate cells upon activation in vitro and in vivo. J Thromb Haemost. 2006 May;4(5):1063-70. METHODS: In this study, we determined the ADAMTS-13 mRNA, protein, and activity in isolated primary HSCs upon activation on a plastic dish and in liver after administration of carbon tetrachloride (CCl (4)) in rats. |
37(0,1,1,7) | Details |