| 17564302 |
Banasik M, Stedeford T, Ueda K, Muro-Cacho C, Su PH, Tanaka S, Harbison RD: Hepatoprotective effects of 6 (5H)-phenanthridinone from chemical-induced centrilobular necrosis. Res Commun Mol Pathol Pharmacol. 2004;115-116:15-20.
The purpose of the present study was to determine whether 6 (5H)-phenanthridinone, a potent inhibitor of PARP-1, could attenuate the hepatotoxicity of carbon tetrachloride (CCl4). |
34(0,1,1,4) |
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| 15686116 |
Su PH, Takehashi M, Tanaka S, Banasik M, Stedeford T, Ueda K, Muro-Cacho C, Harbison RD: Hepatocellular accumulation of poly (ADP-ribose) in male ICR mice treated with a necrogenic dose of carbon tetrachloride. Res Commun Mol Pathol Pharmacol. 2003;113-114:171-9.
In the present study, PARP-1 overactivation was determined by identifying the distribution and accumulation of poly (ADP-ribose) following intraperitoneal administration of a hepatotoxic dose of carbon tetrachloride (572 mg/kg). |
8(0,0,1,3) |
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