Protein Information

Name caspases (protein family or complex)
Synonyms caspase; caspases

Compound Information

Name para-dichlorobenzene
CAS 1,4-dichlorobenzene

Reference List

PubMed Abstract RScore(About this table)
16699520 Kokel D, Li Y, Qin J, Xue D: The nongenotoxic carcinogens naphthalene and para-dichlorobenzene suppress apoptosis in Caenorhabditis elegans. Nat Chem Biol. 2006 Jun;2(6):338-45. Epub 2006 May 14.

In addition, we find that a naphthalene metabolite directly inactivates caspases by oxidizing the active site cysteine residue; this suggests a molecular mechanism by which these chemicals suppress apoptosis.
1(0,0,0,1) Details