Protein Information

Name activator protein 1
Synonyms AP1; Activator protein 1; JUN; Proto oncogene c jun; Protooncogene c jun; Transcription factor AP 1; V jun avian sarcoma virus 17 oncogene homolog; c Jun…

Compound Information

Name ethylene dibromide
CAS 1,2-dibromoethane

Reference List

PubMed Abstract RScore(About this table)
8514261 Coni P, Simbula G, de Prati AC, Menegazzi M, Suzuki H, Sarma DS, Ledda-Columbano GM, Columbano A: Differences in the steady-state levels of c-fos, c-jun and c-myc messenger RNA during mitogen-induced liver growth and compensatory regeneration. Hepatology. 1993 Jun;17(6):1109-16.

The steady-state levels of c-fos, c-jun and c-myc messenger RNA were investigated in rat liver tissue after proliferative stimuli of different nature-namely, compensatory regeneration induced by partial hepatectomy or carbon tetrachloride administration-and direct hyperplasia induced by four different hepatomitogens: lead nitrate, ethylene dibromide, cyproterone acetate and nafenopin.
14(0,0,2,4) Details
10381180 Camandola S, Aragno M, Cutrin JC, Tamagno E, Danni O, Chiarpotto E, Parola M, Leonarduzzi G, Biasi F, Poli G: Liver AP-1 activation due to carbon tetrachloride is potentiated by 1,2-dibromoethane but is inhibited by alpha-tocopherol or gadolinium chloride. Free Radic Biol Med. 1999 May;26(9-10):1108-16.


Our aim was to clarify the role of oxidative imbalance in the activation of the redox-sensitive transcription factor, activator protein-1 (AP-1), which is involved in tissue repair.
1(0,0,0,1) Details