| Name | alcohol dehydrogenase (protein family or complex) |
|---|---|
| Synonyms | ADH; alcohol dehydrogenase; alcohol dehydrogenases |
| Name | ethylene dichloride |
|---|---|
| CAS | 1,2-dichloroethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 7765836 | Janssen DB, van der Ploeg JR, Pries F: Genetics and biochemistry of 1,2-dichloroethane degradation. . Biodegradation. 1994 Dec;5(3-4):249-57. Two other enzymes, the alcohol dehydrogenase and the haloacid dehalogenase, are chromosomally encoded. |
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| 18467461 | Mena-Benitez GL, Gandia-Herrero F, Graham S, Larson TR, McQueen-Mason SJ, French CE, Rylott EL, Bruce NC: Engineering a catabolic pathway in plants for the degradation of 1,2-dichloroethane. Plant Physiol. 2008 Jul;147(3):1192-8. Epub 2008 May 8. DhlA converts 1,2-DCA to 2-chloroethanol, which is then metabolized to the phytotoxic 2-chloroacetaldehyde, then chloroacetic acid, by endogenous plant alcohol dehydrogenase and aldehyde dehydrogenase activities, respectively. |
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| 7500980 | Fossett NG, Byrne BJ, Tucker AB, Arbour-Reily P, Chang S, Lee WR: Mutation spectrum of 2-chloroethyl methanesulfonate in Drosophila melanogaster premeiotic germ cells. Mutat Res. 1995 Oct;331(2):213-24. The 2-chloroethyl methanesulfonate (2ClEMS)-induced alcohol dehydrogenase (Adh) null germline mutation frequency in treated Drosophila melanogaster second instar larval gonia was two orders of magnitude greater than the spontaneous mutation frequency. |
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| 1575500 | van den Wijngaard AJ, van der Kamp KW, van der Ploeg J, Pries F, Kazemier B, Janssen DB: Degradation of 1,2-dichloroethane by Ancylobacter aquaticus and other facultative methylotrophs. Appl Environ Microbiol. 1992 Mar;58(3):976-83. In all strains tested, DCE was degraded by initial hydrolytic dehalogenation to 2-chloroethanol, followed by oxidation by a phenazine methosulfate-dependent alcohol dehydrogenase and an NAD-dependent aldehyde dehydrogenase. |
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