| Name | alkaline phosphatase |
|---|---|
| Synonyms | ALP 1; Alkaline phosphatase; ALPG; ALPPL; ALPPL 2; ALPPL2; GCAP; Germ cell alkaline phosphatase… |
| Name | ethylene oxide |
|---|---|
| CAS | oxirane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 16579687 | Moioli EK, Hong L, Guardado J, Clark PA, Mao JJ: Sustained release of TGFbeta3 from PLGA microspheres and its effect on early osteogenic differentiation of human mesenchymal stem cells. Tissue Eng. 2006 Mar;12(3):537-46. To compare sterilization modalities of microspheres, bFGF was encapsulated in 50:50 PLGA microspheres and subjected to ethylene oxide (EO) gas, radio-frequency glow discharge (RFGD), or ultraviolet (UV) light. Alkaline phosphatase staining intensity was markedly reduced 1 week after exposing hMSC-derived osteogenic cells to TGFbeta3. |
3(0,0,0,3) | Details |
| 15468192 | Richard P, Pollard H, Lanctin C, Bello-Roufai M, Desigaux L, Escande D, Pitard B: Inducible production of erythropoietin using intramuscular injection of block copolymer/DNA formulation. J Gene Med. 2005 Jan;7(1):80-6. METHODS: Plasmids encoding either constitutive human secreted alkaline phosphatase or murine erythropoietin inducible via a Tet-on system were formulated with PE6400 and intramuscularly injected into the mouse tibial anterior muscle. |
2(0,0,0,2) | Details |
| 18830866 | Singh-Joy SD, McLain VC: Safety assessment of poloxamers 101, 105, 108, 122, 123, 124, 181, 182, 183, 184, 185, 188, 212, 215, 217, 231, 234, 235, 237, 238, 282, 284, 288, 331, 333, 334, 335, 338, 401, 402, 403, and 407, poloxamer 105 and poloxamer 182 dibenzoate as used in cosmetics. Int J Toxicol. 2008;27 Suppl 2:93-128. Doses up to 0.5 mg/kg day (-1) for 2 years using rats produced yellow discoloration of the serum, high serum alkaline phosphatase activity, and elevated serum glutamicpyruvic transaminase and glutamic-oxalacetic transaminase activities. The impurities of commercial grade Poloxamer 188, as an example, include low-molecular-weight substances (aldehydes and both formic and acetic acids), as well as 1,4-dioxane and residual ethylene oxide and propylene oxide. |
1(0,0,0,1) | Details |
| 19995620 | Xu W, Ma J, Jabbari E: Material properties and osteogenic differentiation of marrow stromal cells on fiber-reinforced laminated hydrogel nanocomposites. Acta Biomater. 2009 Dec 6. Layers of electrospun poly (l-lactide) fiber mesh coated with a poly (lactide-co-ethylene oxide (PLEOF) hydrogel precursor solution were stacked and pressed together, and crosslinked to produce a laminated fiber-reinforced composite. At days 14 and 21, alkaline phosphatase (ALPase) activity of the laminates was significantly higher than those of the fiber mesh and hydrogel. |
1(0,0,0,1) | Details |
| 16022999 | Hofmann A, Konrad L, Hessmann MH, Kuchle R, Korner J, Rompe JD, Rommens PM: The influence of bone allograft processing on osteoblast attachment and function. J Orthop Res. 2005 Jul;23(4):846-54. Epub 2005 Jan 26. Following processing methods were tested: autoclavation (AUT), low-temperature-plasma sterilisation of demineralised allografts (D-LTP), ethylene oxide sterilisation (EtO), fresh frozen bone (FFB), 80 degrees C-thermodisinfection (80 degrees C), gamma-irradiation (Gamma), chemical solvent disinfection (CSD), and Barrycidal-disinfection (BAR). Tests to confirm the osteoblastic differentiation included histochemical alkaline phosphatase staining and RT-PCR for osteocalcin. |
1(0,0,0,1) | Details |
| 20088700 | Zhang Y, Reddy VJ, Wong SY, Li X, Su B, Ramakrishna S, Lim CT: Enhanced Biomineralization in Osteoblasts on a Novel Electrospun Biocomposite Nanofibrous Substrate of Hydroxyapatite/Collagen/ Tissue Eng Part A. 2010 Mar 1. We show herein that Col-doped HAp/CTS biocomposite (i.e., HAp/Col/CTS) containing 27.8 wt% HAp nanoparticles, 7.2 wt% Col, and 57.8 wt% CTS can be successfully electrospun into nanofibrous form through using small amount (7.2 wt%) of ultrahigh-molecular-weight poly (ethylene oxide) as the fiber-forming additive. In comparison with different controls, significant increments in osteoblast proliferation, alkaline phosphatase expression, and mineral deposition were observed. |
1(0,0,0,1) | Details |
| 20039599 | Nandakumar A, Yang L, Habibovic P, van Blitterswijk C: Coated Electrospun Fiber Matrices as Scaffolds for Bone Tissue Engineering. Langmuir. 2009 Dec 29. In this study, we applied a biomimetic coating method to provide electrospun scaffolds from a block copolymer-poly (ethylene oxide terephthalate)-poly (buthylene terephthalate), with a layer to improve their bioactivity in bone tissue engineering. |
0(0,0,0,0) | Details |
| 19944190 | Kroeze RJ, Helder MN, Roos WH, Wuite GJ, Bank RA, Smit TH: The effect of ethylene oxide, glow discharge and electron beam on the surface characteristics of poly (l-lactide-co-caprolactone) and the corresponding cellular response of adipose stem cells. Acta Biomater. 2009 Nov 26. The alkaline phosphatase activity was significantly higher for the ethylene oxide sterilized PLCL sheet. |
6(0,0,1,1) | Details |