| Name | estrogen receptor |
|---|---|
| Synonyms | ER; ERA; ER alpha; ERalpha; ESR; ESR 1; ESR1; ESRA… |
| Name | methylene chloride |
|---|---|
| CAS | dichloromethane |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 9138628 | O'Connor JC, Cook JC, Van Pelt CS, Arnold SF, Obourn JD: Weak estrogenic activity from continuous-release pellets. Reprod Toxicol. 1997 Jan-Feb;11(1):101-6. In addition, a methylene chloride/DMSO extract of the control pellets promoted expression of a reporter gene controlled by the estrogen receptor and demonstrated competition with 17 for binding to the human estrogen receptor. |
82(1,1,1,2) | Details |
| 9841810 | Meek MD: Ah receptor and estrogen receptor-dependent modulation of gene expression by extracts of diesel exhaust particles. Environ Res. 1998 Nov;79(2):114-21. The ability of a methylene chloride extract of diesel exhaust particle (EDEP) to activate the aryl hydrocarbon receptor (AhR), bind to and activate the estrogen receptor (ER), and induce gene expression mediated via these nuclear receptors was examined in Hepa1c1c7 mouse hepatoma and MCF-7 human breast cancer cells. |
32(0,1,1,2) | Details |
| 11999990 | Muthumbi W, De Boever P, D'Haese I, D'Hooge W, Top EM, Pieters JG, Comhaire F, Verstraete W: Assessment of the estrogenic activity of flue gases from burning processes by means of the yeast based human estrogen receptor (hER) bioassay. Environ Technol. 2002 Mar;23(3):287-91. The modified assay was calibrated using a model estrogenic compound (17-alpha-ethinylestradiol (EE2)) dissolved in methylene chloride at concentrations ranging from 3 ng l (-1) to 3000 ng l (-1). |
2(0,0,0,2) | Details |
| 18277611 | Oh SM, Ryu BT, Chung KH: Identification of estrogenic and antiestrogenic activities of respirable diesel exhaust particles by bioassay-directed fractionation. Arch Pharm Res. 2008 Jan;31(1):75-82. Estrogenic activity of CE and some fractions (F1, F2, F3, F5 and F6) was induced through estrogen receptor (ER)-mediated pathways. |
1(0,0,0,1) | Details |
| 12604836 | Huggett DB, Foran CM, Brooks BW, Weston J, Peterson B, Marsh KE, La Point TW, Schlenk D: Comparison of in vitro and in vivo bioassays for estrogenicity in effluent from North American municipal wastewater facilities. Toxicol Sci. 2003 Mar;72(1):77-83. Attempts to better understand causal factors affecting estrogenicity in municipal wastewater have primarily focused on analytical evaluation of specific chemical estrogens and the use of estrogen receptor (ER) based in vitro assays. Estrogenic activity, as measured by the YES assay, was observed in and/or methylene chloride eluents from C18 extracts in two of the New York treatment facilities and the Texas facility. |
1(0,0,0,1) | Details |