Protein Information

Name LHRH
Synonyms GNRH; GNRH 1; GNRH1; GRH; GnRH associated peptide I; Gonadoliberin I; Gonadorelin; Gonadotropin releasing hormone 1…

Compound Information

Name methylene chloride
CAS dichloromethane

Reference List

PubMed Abstract RScore(About this table)
17643561 Conforti VA, de Avila DM, Cummings NS, Wells KJ, Ulker H, Reeves JJ: The effectiveness of a CpG motif-based adjuvant (CpG ODN 2006) for LHRH immunization. Vaccine. 2007 Aug 29;25(35):6537-43. Epub 2007 Jun 14.

Rats received either ova-LHRH solubilized in urea; lyophilized ova-LHRH; lyophilized ova-LHRH exposed to methylene chloride; or lyophilized ova-LHRH exposed to ethyl acetate.
13(0,0,1,8) Details
11282233 Nicoli S, Santi P, Couvreur P, Couarraze G, Colombo P, Fattal E: Design of triptorelin loaded nanospheres for transdermal iontophoretic administration. Int J Pharm. 2001 Feb 19;214(1-2):31-5.

Triptorelin is a decapeptide analog of luteinizing hormone releasing hormone, currently used for the treatment of sex-hormones dependents diseases.
The encapsulation efficiency varied from 4 to 83% reaching the maximum value when both the internal and the external water phases were brought to pH 7 (isoelectric point of the peptide), methylene chloride was used as solvent of the copolymers and PLGA rich in free carboxylic groups was employed.
1(0,0,0,1) Details