| 17320131 |
Di Renzo F, Cappelletti G, Broccia ML, Giavini E, Menegola E: Boric acid inhibits embryonic histone deacetylases: a suggested mechanism to explain boric acid-related teratogenicity. Toxicol Appl Pharmacol. 2007 Apr 15;220(2):178-85. Epub 2007 Jan 12.
The aim of this study is to verify if boric acid (BA), that induces in rodents malformations similar to those valproic acid and trichostatin A-related, acts through similar mechanisms: HDAC inhibition and histone hyperacetylation. |
36(0,1,1,6) |
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