Protein Information

Name prostate specific antigen
Synonyms NPSA; Prostate specific antigen; novel prostate specific antigen; Prostate specific antigens; novel prostate specific antigens

Compound Information

Name boric acid
CAS

Reference List

PubMed Abstract RScore(About this table)
12481254 Gallardo-Williams MT, Maronpot RR, Wine RN, Brunssen SH, Chapin RE: Inhibition of the enzymatic activity of prostate-specific antigen by boric acid and 3-nitrophenyl boronic acid. Prostate. 2003 Jan 1;54(1):44-9.
 32(0,1,1,2) Details
14713551 Gallardo-Williams MT, Chapin RE, King PE, Moser GJ, Goldsworthy TL, Morrison JP, Maronpot RR: Boron supplementation inhibits the growth and local expression of IGF-1 in human prostate adenocarcinoma (LNCaP) tumors in nude mice. Toxicol Pathol. 2004 Jan-Feb;32(1):73-8.

Prostate-specific antigen (PSA) is a serine protease and one of the most abundant proteins secreted by the human prostate epithelium.
In this study we have addressed the use of boric acid as a PSA inhibitor in an animal study.		 1(0,0,0,1) Details