| Name | Tamm Horsfall glycoprotein |
|---|---|
| Synonyms | ADMCKD 2; ADMCKD2; MCKD 2; MCKD2; FJHN; HNFJ; THGP; THP… |
| Name | diatomaceous earth |
|---|---|
| CAS | diatomite |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 2500486 | Serafini-Cessi F, Bellabarba G, Malagolini N, Dall'Olio F: Rapid isolation of Tamm-Horsfall glycoprotein (uromodulin) from human urine. J Immunol Methods. 1989 Jun 21;120(2):185-9. An isolation method for Tamm-Horsfall protein is described which is based on the observation that a diatomaceous earth filter is able to retain most of the glycoprotein present in urine and that the glycoprotein is easily desorbed from the filter by deionized water. |
3(0,0,0,3) | Details |
| 9693939 | Olczak T, Kubicz A, Kokot F, Dulawa J: Tamm-Horsfall protein isolated from urine of pregnant and non-pregnant women has similar oligosaccharides. Eur J Clin Invest. 1998 Jun;28(6):475-82. BACKGROUND: Differences in the immunosuppressive activity of Tamm-Horsfall protein and uromodulin claimed by many investigators are controversial. METHODS: We isolated urinary glycoproteins from 18 non-pregnant (THP) and 12 pregnant (UM) women using the same method (adsorption on diatomaceous earth) and performed comparative studies including monocarbohydrate analysis and tests of reactivity with lectins, cytokines and serum proteins. |
2(0,0,0,2) | Details |
| 12270772 | Cavallone D, Malagolini N, Frasca GM, Stefoni S, Serafini-Cessi F: Salt-precipitation method does not isolate to homogeneity Tamm-Horsfall glycoprotein from urine of proteinuric patients and pregnant women. Clin Biochem. 2002 Jul;35(5):405-10. OBJECTIVE: Assessment of the degree of purification of Tamm-Horsfall glycoprotein from anomalous urine. DESIGN AND METHODS: Two methods have been compared: the method of Tamm & Horsfall (T&H; method) consisting in the precipitation of THP by the addition to urine of NaCl up to 0.58 mol/L and the filtration of urine through a diatomaceous earth filter (DEF method) in which THP is selectively trapped because of its gelation/aggregation tendency. |
1(0,0,0,1) | Details |