Protein Information

Name hemoglobin (protein family or complex)
Synonyms Hemoglobin; Hemoglobins

Compound Information

Name silica gel
CAS silica gel

Reference List

PubMed Abstract RScore(About this table)
17364472 Bruno S, Ronda L, Bettati S, Mozzarelli A: Trapping hemoglobin in rigid matrices: fine tuning of oxygen binding properties by modulation of encapsulation protocols. Artif Cells Blood Substit Immobil Biotechnol. 2007;35(1):69-79.

We applied this approach by entrapping hemoglobin in wet nanoporous silica gel, in the presence and absence of allosteric effectors.
34(0,1,1,4) Details
16332093 Sottini S, Abbruzzetti S, Spyrakis F, Bettati S, Ronda L, Mozzarelli A, Viappiani C: Geminate rebinding in R-state hemoglobin: kinetic and computational evidence for multiple hydrophobic pockets. J Am Chem Soc. 2005 Dec 14;127(49):17427-32.

We show that the time course of CO rebinding to human hemoglobin also exhibits a biphasic geminate rebinding when the protein is entrapped in wet nanoporous silica gel.
8(0,0,1,3) Details
16852394 Sottini S, Abbruzzetti S, Viappiani C, Bettati S, Ronda L, Mozzarelli A: Evidence for two geminate rebinding states following laser photolysis of R state hemoglobin encapsulated in wet silica gels. J Phys Chem B. 2005 Jun 16;109(23):11411-3.

The analysis of the rebinding kinetics using a maximum entropy method allowed the identification of two distinct rebinding states within the protein matrix, which become populated under conditions of increased viscosity in a silica gel at high glycerol concentration.
2(0,0,0,2) Details
17344073 Ding MJ, Xu SW, Zhang J, Wang Q, Chang Y, Chen F, Zeng YJ: Trauma to erythrocytes induced by long term in vitro pumping using a roller pump. Cell Biol Int. 2007 Aug;31(8):763-7. Epub 2007 Jan 25.

Each blood bag was subject to pumping in a closed circuit, which was composed of silica gel tubes and a roller pump.
Free hemoglobin (FHb), platelets (PLT), erythrocyte fragility (EF), and morphological analysis of erythrocytes observed under scanning electron microscope were measured to evaluate the impact of trauma on erythrocytes.
1(0,0,0,1) Details