Protein Information

Name beta secretase
Synonyms ASP2; App beta secretase; Asp 2; Asp2; Aspartyl protease 2; BACE; BACE 1; BACE1…

Compound Information

Name silica gel
CAS silica gel

Reference List

PubMed Abstract RScore(About this table)
16114494 Lee HJ, Seong YH, Bae KH, Kwon SH, Kwak HM, Nho SK, Kim KA, Hur JM, Lee KB, Kang YH, Song KS: Beta-secretase (BACE1) inhibitors from Sanguisorbae Radix. Arch Pharm Res. 2005 Jul;28(7):799-803.

In the course of screening anti-dementia agents from natural products, two beta-secretase (BACE1) inhibitors were isolated from the ethyl acetate soluble fraction of Sanguisorbae Radix by the activity-guided purification using silica gel, Sephadex LH-20, and RP-HPLC.
34(0,1,1,4) Details