Protein Information

Name carbonic anhydrase
Synonyms CA IX; CA1; Carbonic anhydrase I; CA2; CAII; Carbonic anhydrase II; Carbonic dehydratase; Carbonic anhydrase III…

Compound Information

Name sodium thiocyanate
CAS sodium thiocyanate

Reference List

PubMed Abstract RScore(About this table)
2996300 Vega FV, Olaisson H, Mardh S: Distribution of carbonic anhydrase in cells and membranes isolated from pig gastric mucosa. Acta Physiol Scand. 1985 Aug;124(4):573-9.

6(0,0,0,6) Details
17242477 Kotwica J, Ciuk MA, Joachimiak E, Rowinski S, Cymborowski B, Bebas P: Carbonic anhydrase activity in the vas deferens of the cotton leafworm - Spodoptera littoralis (Lepidoptera: Noctuidae) controlled by circadian clock. J Physiol Pharmacol. 2006 Nov;57 Suppl 8:107-23.

Conversely, the application of CA inhibitors, acetazolamide and sodium thiocyanate, in conjunction with an analysis of H+-ATPase activity in the acidification the UVD environment shows that CA most likely does not play a direct role in the regulation of the pH in this organ.
2(0,0,0,2) Details
2573753 Colombo M, Fort M, Farre AJ: Isolated gastric mucosa: an early approach to the study of the mechanism of action of gastric antisecretory agents. Methods Find Exp Clin Pharmacol. 1989 Oct;11(10):621-34.

The technique and its application to a series of known antisecretory agents--cimetidine, ranitidine, timoprazole and omeprazole--and to other substances with antisecretory activity such as sodium thiocyanate, verapamil, trimipramine and imipramine, is described.
In order to illustrate the activity of the aforementioned substances in the more classic tests of antisecretory activity, an in vivo test of inhibition of gastric secretion in pylorus-ligated rats and the in vitro tests of H2-receptor blocking activity (isolated guinea-pig atrium), anticholinergic activity (isolated guinea-pig ileum) and carbonic anhydrase (canine blood) were included.
1(0,0,0,1) Details
162573 Suzuki S: The presence and properties of Mg2+-HCO3 (-)-stimulated and SCN (-)-inhibited ATPase in mouse kidney and some relationships between ATPase and carbonic anhydrase. Comp Biochem Physiol B. 1978;59(1):27-36.

1(0,0,0,1) Details