Name | GAL4 |
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Synonyms | Antigen NY CO 27; GAL 4; GAL4; Galectin 4; L 36 lactose binding protein; L36LBP; LGALS 4; LGALS4… |
Name | methoxyfenozide |
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CAS | 3-methoxy-2-methylbenzoic acid 2-(3,5-dimethylbenzoyl)-2-(1,1-dimethylethyl)hydrazide |
PubMed | Abstract | RScore(About this table) | |
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16412090 | Tavva VS, Dinkins RD, Palli SR, Collins GB: Development of a methoxyfenozide-responsive gene switch for applications in plants. Plant J. 2006 Feb;45(3):457-69. The receptor constructs were prepared by fusing DEF domains (hinge region plus ligand-binding domain) of CfEcR to the GAL4 DNA-binding domain and EF domains (ligand-binding domain) of ultraspiracle from Choristoneura fumiferana (CfUSP) or RXR from Locusta migratoria (LmRXR), Mus musculus (MmRXR) or Homo sapiens (HsRXR) to the VP16 activation domain. |
2(0,0,0,2) | Details |
12437077 | Unger E, Cigan AM, Trimnell M, Xu RJ, Kendall T, Roth B, Albertsen M: A chimeric ecdysone receptor facilitates methoxyfenozide-dependent restoration of male fertility in ms45 maize. Transgenic Res. 2002 Oct;11(5):455-65. A high frequency of phenotypic complementation was observed when either C1-GAL4 or VP16-GAL4 activators were transcribed by promoters that expressed at a stage of anther development that precedes the early vacuolate stage of microsporogenesis. |
2(0,0,0,2) | Details |
12650528 | Padidam M, Gore M, Lu DL, Smirnova O: Chemical-inducible, ecdysone receptor-based gene expression system for plants. Transgenic Res. 2003 Feb;12(1):101-9. We have developed an inducible gene expression system with potential for field application using the ecdysone receptor (EcR) from the spruce budworm and the non-steroidal EcR agonist, methoxyfenozide. Chimeric transcription activators were constructed with EcR ligand binding domain, GAL4 and LexA DNA binding domains, and VP16 activation domain. |
1(0,0,0,1) | Details |
17570490 | Tavva VS, Palli SR, Dinkins RD, Collins GB: Applications of EcR gene switch technology in functional genomics. Arch Insect Biochem Physiol. 2007 Jul;65(3):164-79. The ecdysone receptor gene switch is one of the best inducible gene regulation systems available, because the chemical, methoxyfenozide, required for its regulation is registered for field use. In a two-hybrid switch format, the GAL4 DNA binding domain (GAL4 DBD) was fused to the ligand binding domain (LBD) of the Choristoneura fumiferana ecdysone receptor (CfEcR); and, the VP16 activation domain (VP16 AD) was fused to the LBD of Locust migratoria retinoid X receptor (LmRXR). |
1(0,0,0,1) | Details |