Protein Information

Name AP 1 (protein family or complex)
Synonyms AP 1; AP 1 complex; AP1; Adapter related protein complex 1

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
19063868 Marrero MB, Bencherif M: Convergence of alpha 7 nicotinic acetylcholine receptor-activated pathways for anti-apoptosis and anti-inflammation: central role for JAK2 activation of STAT3 and NF-kappaB. Brain Res. 2009 Feb 23;1256:1-7. Epub 2008 Nov 27.

In this study, we investigated the effects of inhibiting the alpha7 nAChR-JAK2 pro-survival cascade on the nicotine-induced production of the survival factor Bcl-2 and the transcriptional activation of NF-kappaB, AP-1, STAT1, STAT3, and STAT5.
62(0,2,2,2) Details