| Name | MAOA |
|---|---|
| Synonyms | Amine oxidase [flavin containing] A; MAO A; MAOA; Monoamine oxidase A; Monoamine oxidase A variant; Monoamine oxidase type A; Monoamine oxidase As; Monoamine oxidase A variants… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20026027 | Arib O, Rat P, Molimard R, Chait A, Faure P, de Beaurepaire R: Electrophysiological characterization of harmane-induced activation of mesolimbic neurons. Eur J Pharmacol. 2010 Mar 10;629(1-3):47-52. Epub 2009 Dec 21. The effects of harmane (2mg/kg) and norharmane (2mg/kg), were compared to those of nicotine (11microg/kg), of (0.5mg/kg), of the monoamine-oxidase-A inhibitor befloxatone (0.12mg/kg), and of the monoamine-oxidase-B inhibitor selegiline (0.5mg/kg). |
31(0,1,1,1) | Details |
| 19184649 | Sharma A, Brody AL: In vivo brain imaging of human exposure to nicotine and tobacco. Handb Exp Pharmacol. 2009;(192):145-71. Responses to chronic nicotine/cigarette exposure include decreased monoamine oxidase (MAO) A and B activity in the basal ganglia and a reduction in alpha4beta2 nicotinic acetylcholine receptor (nAChR) availability in the thalamus and putamen (accompanied by an overall upregulation of these receptors). |
31(0,1,1,1) | Details |
| 19415821 | Tang X, Guo S, Sun H, Song X, Jiang Z, Sheng L, Zhou D, Hu Y, Chen D: Gene-gene interactions of CYP2A6 and MAOA polymorphisms on smoking behavior in Chinese male population. Pharmacogenet Genomics. 2009 May;19(5):345-52. OBJECTIVES: Nicotine is the major psychoactive ingredient in tobacco, and is responsible for dependence through the nicotine-stimulated reward pathway mediated by the central dopaminergic system. |
4(0,0,0,4) | Details |
| 19777560 | Philibert RA, Beach SR, Gunter TD, Brody GH, Madan A, Gerrard M: The effect of smoking on MAOA promoter methylation in DNA prepared from lymphoblasts and whole blood. Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 5;153B(2):619-28. |
3(0,0,0,3) | Details |
| 19247474 | Caporaso N, Gu F, Chatterjee N, Sheng-Chih J, Yu K, Yeager M, Chen C, Jacobs K, Wheeler W, Landi MT, Ziegler RG, Hunter DJ, Chanock S, Hankinson S, Kraft P, Bergen AW: Genome-wide and candidate gene association study of cigarette smoking behaviors. PLoS One. 2009;4(2):e4653. Epub 2009 Feb 27. Besides CHRNA3 and CHRNA5, MAOA was associated with CPDBI (gene-level p <5.4x10 (-5)), our analysis provides independent replication of the association between the chr15q25.1 region and smoking intensity and data for multiple other loci associated with smoking behavior that merit further follow-up. |
1(0,0,0,1) | Details |
| 19142115 | Leroy C, Bragulat V, Berlin I, Gregoire MC, Bottlaender M, Roumenov D, Dolle F, Bourgeois S, Penttila J, Artiges E, Martinot JL, Trichard C: Cerebral monoamine oxidase A inhibition in tobacco smokers confirmed with PET and [11C] befloxatone. J Clin Psychopharmacol. 2009 Feb;29(1):86-8. |
1(0,0,0,1) | Details |