Protein Information

Name fms like tyrosine kinase 1
Synonyms FLT; Tyrosine protein kinase receptor; FLT1; FMS related tyrosine kinase 1; FRT; Flt 1; Fms like tyrosine kinase 1; Fms related tyrosine kinase 1 (Vascular endothelial growth factor/vascular permeability factor receptor) variant…

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
20223446 Mimura K, Tomimatsu T, Sharentuya N, Tskitishvili E, Kinugasa-Taniguchi Y, Kanagawa T, Kimura T: Nicotine restores endothelial dysfunction caused by excess sFlt1 and sEng in an in vitro model of preeclamptic vascular endothelium: a possible therapeutic role of nicotinic acetylcholine receptor (nAChR) agonists for preeclampsia. Am J Obstet Gynecol. 2010 Mar 10.

OBJECTIVE: In this study we tested the hypothesis that nicotine restores proangiogenic functions to endothelial cells pretreated with soluble fms-like tyrosine kinase 1 and/or soluble endoglin.		 119(1,2,3,4) Details