| Name | corticotropin releasing factor receptors |
|---|---|
| Synonyms | CRF 1; CRF R; CRF1; CRFR; CRFR 1; CRFR1; CRH R 1; CRH R1h… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19217073 | Bruijnzeel AW, Prado M, Isaac S: Corticotropin-releasing factor-1 receptor activation mediates nicotine withdrawal-induced deficit in brain reward function and stress-induced relapse. Biol Psychiatry. 2009 Jul 15;66(2):110-7. Epub 2009 Feb 12. Previous research has shown that blockade of corticotropin-releasing factor (CRF) receptors with a nonspecific CRF1/CRF2 receptor antagonist prevents the deficit in brain reward function associated with nicotine withdrawal and stress-induced reinstatement of extinguished nicotine-seeking in rats. |
62(0,2,2,2) | Details |
| 19145226 | Marcinkiewcz CA, Prado MM, Isaac SK, Marshall A, Rylkova D, Bruijnzeel AW: Corticotropin-releasing factor within the central nucleus of the amygdala and the nucleus accumbens shell mediates the negative affective state of nicotine withdrawal in rats. Neuropsychopharmacology. 2009 Jun;34(7):1743-52. Epub 2009 Jan 14. The administration of the nonspecific CRF1/2 receptor antagonist D- CRF ((12-41)) into the CeA and the Nacc shell prevented the mecamylamine-induced elevations in brain reward thresholds in the nicotine-dependent rats. |
31(0,1,1,1) | Details |
| 19878140 | Nelson EC, Agrawal A, Pergadia ML, Wang JC, Whitfield JB, Saccone FS, Kern J, Grant JD, Schrage AJ, Rice JP, Montgomery GW, Heath AC, Goate AM, Martin NG, Madden PA: H2 haplotype at chromosome 17q21.31 protects against childhood sexual abuse-associated risk for consumption and dependence. Addict Biol. 2010 Jan;15(1):1-11. Epub . CRHR1 and at least four other genes are located at 17q21.31 in an extremely large block of high linkage disequilibrium resulting from a local chromosomal inversion; the minor allele of rs1876831 is contained within the H2 haplotype. Here, we examine whether G x E interactions involving this haplotype and childhood sexual abuse (CSA) are associated with risk for consumption and dependence in Australian participants (n = 1128 respondents from 476 families) of the Nicotine Addiction Genetics project. |
1(0,0,0,1) | Details |
| 20147556 | Plaza-Zabala A, Martin-Garcia E, de Lecea L, Maldonado R, Berrendero F: Hypocretins regulate the anxiogenic-like effects of nicotine and induce reinstatement of nicotine-seeking behavior. J Neurosci. 2010 Feb 10;30(6):2300-10. |
0(0,0,0,0) | Details |