Protein Information

Name VILIP 1
Synonyms 21 kDa CABP; HLP 3; HLP3; HPCAL 3; HPCAL3; HUVISL 1; HUVISL1; Hippocalcin like protein 3…

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
19063970 Zhao CJ, Noack C, Brackmann M, Gloveli T, Maelicke A, Heinemann U, Anand R, Braunewell KH: Neuronal Ca2+ sensor VILIP-1 leads to the upregulation of functional alpha4beta2 nicotinic acetylcholine receptors in hippocampal neurons. Mol Cell Neurosci. 2009 Feb;40(2):280-92. Epub 2008 Nov 19.

The neuronal Ca2+-sensor protein VILIP-1, known to affect clathrin-dependent receptor trafficking, has been shown to interact with the cytoplasmic loop of the alpha4-subunit of the alpha4beta2 nicotinic acetylcholine receptor (nAChR), which is the most abundant nAChR subtype with high-affinity for nicotine in the brain.
35(0,1,1,5) Details