| Name | EP1 |
|---|---|
| Synonyms | EP1; PGE receptor EP1 subtype; PTGER 1; Prostaglandin E2 receptor EP1 subtype; Prostanoid EP1 receptor; PGE receptor EP1 subtypes; Prostaglandin E2 receptor EP1 subtypes… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19481556 | Grinevich VP, Papke RL, Lippiello PM, Bencherif M: Atypical antipsychotics as noncompetitive inhibitors of alpha4beta2 and alpha7 neuronal nicotinic receptors. Neuropharmacology. 2009 Aug;57(2):183-91. Epub 2009 May 28. However, Rb (+) efflux evoked either by nicotine or the selective alpha4beta2 agonist TC-1827 from alpha4beta2 receptors expressed in SH-EP1 cells and nicotine-evoked [(3) H]- release from rat striatal synaptosomes were non-competitively inhibited by all of the antipsychotics. |
81(1,1,1,1) | Details |
| 19732285 | Hosur V, Leppanen S, Abutaha A, Loring RH: Gene regulation of alpha4beta2 nicotinic receptors: microarray analysis of nicotine-induced receptor up-regulation and anti-inflammatory effects. J Neurochem. 2009 Nov;111(3):848-58. Epub 2009 Sep 1. In a microarray analysis, 10 muM nicotine altered expression of 41 genes at 0.25, 1, 8 and 24 h in halpha4beta2 SH-EP1 cells. |
6(0,0,1,1) | Details |
| 19183258 | Zheng C, Wang MY, Liu Q, Wakui M, Whiteaker P, Lukas RJ, Wu J: U18666A, a -inhibition agent, modulates human neuronal nicotinic acetylcholine receptors heterologously expressed in SH-EP1 cell line. J Neurochem. 2009 Mar;108(6):1526-38. Epub 2009 Feb 16. U18666A suppresses both peak and steady state components of whole-cell currents mediated by human alpha4beta2-nAChRs in response to nicotine. |
2(0,0,0,2) | Details |
| 19498421 | Yu KD, Liu Q, Wu J, Lukas RJ: Kinetics of desensitization and recovery from desensitization for human alpha4beta2-nicotinic acetylcholine receptors stably expressed in SH-EP1 cells. Acta Pharmacol Sin. 2009 Jun;30(6):805-17. For a given duration of agonist exposure, recovery from desensitization induced by nicotine was slower than recovery from -induced desensitization. |
2(0,0,0,2) | Details |