| Name | CD4 |
|---|---|
| Synonyms | CD4; CD4 antigen (p55); CD4 molecule; CD4mut; T cell antigen T4/LEU3; T cell surface glycoprotein CD4; T cell surface antigen T4/Leu 3; T cell surface glycoprotein CD4 precursor… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19846875 | Nizri E, Irony-Tur-Sinai M, Lory O, Orr-Urtreger A, Lavi E, Brenner T: Activation of the cholinergic anti-inflammatory system by nicotine attenuates neuroinflammation via suppression of Th1 and Th17 responses. J Immunol. 2009 Nov 15;183(10):6681-8. Epub 2009 Oct 21. In vivo, administration of nicotine (2 mg/kg s.c.) suppressed the severity of CD4 (+) T cell-mediated disease experimental autoimmune encephalomyelitis. alpha7 (-/-) mice were refractory to nicotine treatment, although disease severity in those animals was reduced, due to impairment in Ag presentation. |
83(1,1,1,3) | Details |
| 19887104 | Karimi K, Bienenstock J, Wang L, Forsythe P: The vagus nerve modulates CD4+ T cell activity. Brain Behav Immun. 2010 Feb;24(2):316-23. Epub 2009 Nov 1. Cell responses were restored to control levels following the administration of nicotine and the treatment of non-vagotomized animals with a nicotinic receptor antagonist could mimic the effect of vagotomy. |
2(0,0,0,2) | Details |