Protein Information

Name CD11c
Synonyms CD11C; CD11c; CD11c antigen; ITGAX; Integrin alpha X; Integrin alpha X precursor; Leu M5; CD11cs…

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
19155522 Shi FD, Piao WH, Kuo YP, Campagnolo DI, Vollmer TL, Lukas RJ: Nicotinic attenuation of central nervous system inflammation and autoimmunity. J Immunol. 2009 Feb 1;182(3):1730-9.

In the CNS, nicotine exposure selectively reduces numbers of CD11c (+) dendritic and CD11b (+) infiltrating monocytes and resident microglial cells and down-regulates the expression of MHC class II, CD80, and CD86 molecules on these cells.
81(1,1,1,1) Details