Protein Information

Name CRF2 receptor
Synonyms CRF 2 beta; CRF 2; CRF R 2; CRF2; CRF2 receptor; CRF2R; CRFR 2; CRFR2…

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
19217073 Bruijnzeel AW, Prado M, Isaac S: Corticotropin-releasing factor-1 receptor activation mediates nicotine withdrawal-induced deficit in brain reward function and stress-induced relapse. Biol Psychiatry. 2009 Jul 15;66(2):110-7. Epub 2009 Feb 12.

Previous research has shown that blockade of corticotropin-releasing factor (CRF) receptors with a nonspecific CRF1/CRF2 receptor antagonist prevents the deficit in brain reward function associated with nicotine withdrawal and stress-induced reinstatement of extinguished nicotine-seeking in rats.
62(0,2,2,2) Details