Protein Information

Name CD68
Synonyms CD68; GP110; CD68 antigen; CD68 molecule; Macrophage antigen CD68; Macrosialin; Macrosialin precursor; SCARD 1…

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
19416779 Hirschburger M, Zakrzewicz A, Kummer W, Padberg W, Grau V: Nicotine attenuates macrophage infiltration in rat lung allografts. J Heart Lung Transplant. 2009 May;28(5):493-500.

RESULTS: Nicotine treatment resulted in a marked reduction in lung allograft infiltration by CD68-like antigen (+) alveolar and tissue macrophages, whereas resident mature macrophages (CD163 (+)) and T cells remained unchanged.
81(1,1,1,1) Details
20163570 Sorensen LT, Toft B, Rygaard J, Ladelund S, Teisner B, Gottrup F: Smoking attenuates wound inflammation and proliferation while smoking cessation restores inflammation but not proliferation. Wound Repair Regen. 2010 Feb 16.

The smokers were then randomized to continuous smoking or abstinence with a transdermal nicotine patch or a placebo patch.
All excised tissue was stained with hematoxylin-eosin and immunohistochemically for macrophages (CD68), procollagen 1 N-terminal propeptide (PINP) in fibroblasts, and endothelial cells (CD31).
1(0,0,0,1) Details