| Name | 5 HT 1A |
|---|---|
| Synonyms | 5 HT 1A; serotonin receptor; 5 HT1A; 5 hydroxytryptamine (serotonin) receptor 1A; 5 hydroxytryptamine 1A receptor; 5HT1A; ADRB2RL1; ADRBRL 1… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19372687 | Slotkin TA, Seidler FJ: Nicotine exposure in adolescence alters the response of systems to nicotine administered subsequently in adulthood. Dev Neurosci. 2009;31(1-2):58-70. Epub 2009 Apr 17. We gave nicotine to adolescent rats (postnatal days, PD, 30-47), simulating plasma levels in smokers, and then examined the subsequent effects of nicotine given again in young adulthood (PD 90-107), focusing on 5-HT (1A) and 5-HT (2) receptors and the 5-HT transporter during nicotine treatment (PD 105) and withdrawal (PD 110, 120, 130), and long-term changes (PD 180). |
81(1,1,1,1) | Details |
| 19176807 | Lanteri C, Hernandez Vallejo SJ, Salomon L, Doucet EL, Godeheu G, Torrens Y, Houades V, Tassin JP: Inhibition of monoamine oxidases desensitizes 5-HT1A autoreceptors and allows nicotine to induce a neurochemical and behavioral sensitization. J Neurosci. 2009 Jan 28;29(4):987-97. |
63(0,2,2,3) | Details |
| 19729586 | Duncan JR, Garland M, Myers MM, Fifer WP, Yang M, Kinney HC, Stark RI: Prenatal nicotine-exposure alters fetal autonomic activity and medullary neurotransmitter receptors: implications for sudden infant death syndrome. J Appl Physiol. 2009 Nov;107(5):1579-90. Epub 2009 Sep 3. These changes in heart rate variability were associated with increased 5-HT (1A) receptor binding in the raphe obscurus (P = 0.04) and increased nicotinic receptor binding in the raphe obscurus and vagal complex (P < 0.05) in the nicotine-exposed animals compared with controls (n = 6). |
31(0,1,1,1) | Details |
| 19452140 | Andreasen JT, Nielsen EO, Redrobe JP: Chronic oral nicotine increases brain [3H] epibatidine binding and responsiveness to antidepressant drugs, but not nicotine, in the mouse forced swim test. Psychopharmacology. 2009 Aug;205(3):517-28. Epub 2009 May 12. Additionally, 8-OH-DPAT- and clonidine-induced hypothermia was tested in vehicle- and nicotine-pretreated mice, as a measure of 5-HT (1A) and alpha (2)-adrenoceptor function, respectively. |
31(0,1,1,1) | Details |
| 20097312 | Xia L, Leiter JC, Bartlett D Jr: Gestational nicotine exposure exaggerates hyperthermic enhancement of laryngeal chemoreflex in rat pups. Respir Physiol Neurobiol. 2010 Apr 15;171(1):17-21. Epub 2010 Jan 25. Nicotine was infused in pregnant rats via implanted osmotic minipumps (6.5mg/kg per day) from gestational day 3 (G3) until G21, the day of delivery. |
6(0,0,1,1) | Details |