Protein Information

Name Prostate stem cell antigen
Synonyms PSCA; Prostate stem cell antigen; Prostate stem cell antigen precursor; UNQ206/PRO232; Prostate stem cell antigens; Prostate stem cell antigen precursors

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
19940180 Hruska M, Keefe J, Wert D, Tekinay AB, Hulce JJ, Ibanez-Tallon I, Nishi R: Prostate stem cell antigen is an endogenous lynx1-like prototoxin that antagonizes alpha7-containing nicotinic receptors and prevents programmed cell death of parasympathetic neurons. J Neurosci. 2009 Nov 25;29(47):14847-54.

Misexpressing PSCA before cell death in the ciliary ganglion blocks alpha7-nAChR activation by nicotine and rescues the choroid subpopulation from dying.
35(0,1,1,5) Details