| Name | monoamine oxidase |
|---|---|
| Synonyms | Adrenalin oxidase; Amine oxidase; Amine oxidase [flavin containing] B; MAO B; MAOB; Monoamine oxidase; Monoamine oxidase B; Monoamine oxidase type B… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19176807 | Lanteri C, Hernandez Vallejo SJ, Salomon L, Doucet EL, Godeheu G, Torrens Y, Houades V, Tassin JP: Inhibition of monoamine oxidases desensitizes 5-HT1A autoreceptors and allows nicotine to induce a neurochemical and behavioral sensitization. J Neurosci. 2009 Jan 28;29(4):987-97. |
62(0,2,2,2) | Details |
| 20069419 | Villegier AS, Gallager B, Heston J, Belluzzi JD, Leslie FM: Age influences the effects of nicotine and monoamine oxidase inhibition on mood-related behaviors in rats. Psychopharmacology. 2010 Jan 14. |
62(0,2,2,2) | Details |
| 20026027 | Arib O, Rat P, Molimard R, Chait A, Faure P, de Beaurepaire R: Electrophysiological characterization of harmane-induced activation of mesolimbic neurons. Eur J Pharmacol. 2010 Mar 10;629(1-3):47-52. Epub 2009 Dec 21. The effects of harmane (2mg/kg) and norharmane (2mg/kg), were compared to those of nicotine (11microg/kg), of (0.5mg/kg), of the monoamine-oxidase-A inhibitor befloxatone (0.12mg/kg), and of the monoamine-oxidase-B inhibitor selegiline (0.5mg/kg). |
31(0,1,1,1) | Details |
| 19491139 | Frishman WH: Smoking cessation pharmacotherapy. Ther Adv Cardiovasc Dis. 2009 Aug;3(4):287-308. Epub 2009 Jun 2. First-line therapies include nicotine replacement, and varenicline, a partial nicotine antagonist. Additional treatment strategies with less proven efficacy include monoamine oxidase inhibitors, selective reuptake inhibitors, opioid receptor antagonists, bromocriptine, anti-anxiety drugs, nicotinic receptor antagonists (e.g. mecamylamine) and tablets. |
1(0,0,0,1) | Details |
| 20006620 | Kachalova GS, Bourenkov GP, Mengesdorf T, Schenk S, Maun HR, Burghammer M, Riekel C, Decker K, Bartunik HD: Crystal structure analysis of free and substrate-bound 6-- oxidase from Arthrobacter nicotinovorans. J Mol Biol. 2010 Feb 26;396(3):785-99. Epub 2009 Dec 16. The pathway for oxidative degradation of nicotine in Arthrobacter nicotinovorans includes two genetically and structurally unrelated flavoenzymes, 6-hydroxy- oxidase (6HLNO) and 6-- oxidase, which act with absolute stereospecificity on the L- and D-forms, respectively, of 6--nicotine. The overall structure of each subunit of the 6HLNO homodimer and the folds of the individual domains are closely similar as in eukaryotic monoamine oxidases. |
1(0,0,0,1) | Details |
| 19142115 | Leroy C, Bragulat V, Berlin I, Gregoire MC, Bottlaender M, Roumenov D, Dolle F, Bourgeois S, Penttila J, Artiges E, Martinot JL, Trichard C: Cerebral monoamine oxidase A inhibition in tobacco smokers confirmed with PET and [11C] befloxatone. J Clin Psychopharmacol. 2009 Feb;29(1):86-8. The inhibition of cerebral monoamine oxidases (MAOs) by cigarette smoke components could participate to the tobacco addiction. |
1(0,0,0,1) | Details |
| 19939587 | Weinberger AH, Reutenauer EL, Jatlow PI, O'Malley SS, Potenza MN, George TP: A double-blind, placebo-controlled, randomized clinical trial of oral selegiline hydrochloride for smoking cessation in nicotine-dependent cigarette smokers. Drug Alcohol Depend. 2010 Mar 1;107(2-3):188-95. Epub 2009 Nov 24. AIM: The primary aim of this study was to determine the safety and efficacy of the monoamine oxidase-B (MAO-B) inhibitor selegiline hydrochloride (SEL, l-Deprenyl; Eldepryl) as an aid for smoking cessation in cigarette smokers. |
1(0,0,0,1) | Details |
| 19496753 | Escobar-Chavez JJ, Merino V, Lopez-Cervantes M, Rodriguez-Cruz IM, Quintanar-Guerrero D, Ganem-Quintanar A: The use of iontophoresis in the administration of nicotine and new non-nicotine drugs through the skin for smoking cessation. Curr Drug Discov Technol. 2009 Sep;6(3):171-85. Epub 2009 Sep 1. Other therapeutic drugs that are under development include rimonabant, mecamylamine, monoamine oxidase inhibitors, and D3 receptor antagonists. |
1(0,0,0,1) | Details |