| Name | protein kinase C (protein family or complex) |
|---|---|
| Synonyms | Protein kinase C; PKC |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19729077 | Jeong GS, Lee SH, Jeong SN, Kim YC, Kim EC: Anti-inflammatory effects of on nicotine- and lipopolysaccharide-stimulated human periodontal ligament cells via heme oxygenase-1. Int Immunopharmacol. 2009 Nov;9(12):1374-80. Epub 2009 Sep 1. Treatment with inhibitors of the phosphoinositide 3-kinase, MAPKs, p38, and JNK, as well as a protein kinase C inhibitor, blocked the anti-inflammatory effects of in nicotine- and LPS-treated cells. |
31(0,1,1,1) | Details |
| 19247191 | Hu CZ, Cao YL, Huo HY, Zhao WH, Hu J: Inhibitory effect of ghrelin on nicotine-induced VCAM-1 expression in human umbilical vein endothelial cells. J Cardiovasc Pharmacol. 2009 Mar;53(3):241-5. We examined nicotine-induced VCAM-1 expression in human umbilical vein endothelial cells pretreated with ghrelin and detected the activity of protein kinase C (PKC), p38 mitogen-activated protein kinase (p38 MAPK), and nuclear factor (NF)-kappaB. |
6(0,0,1,1) | Details |
| 20132834 | Garcia-Rates S, Camarasa J, Sanchez-Garcia AI, Gandia L, Escubedo E, Pubill D: The effects of 3,4-methylenedioxymethamphetamine (MDMA) on nicotinic receptors: Intracellular increase, calpain/caspase 3 activation, and functional upregulation. Toxicol Appl Pharmacol. 2010 Feb 2. Sustained entry and calpain activation could favor the activation of Ca (2+)-dependent enzymes such as protein kinase C and synthase, which are involved in the generation of ROS and the blockade of the dopamine transporter. It also concentration-dependently inhibited the response induced by nicotine, and the specific alpha7 agonist PNU 282987 with IC (50) values in the low micromolar range. |
1(0,0,0,1) | Details |
| 19494136 | Buttigieg J, Brown S, Holloway AC, Nurse CA: Chronic nicotine blunts hypoxic sensitivity in perinatal rat chromaffin cells via upregulation of KATP channels: role of alpha7 nicotinic acetylcholine receptor and hypoxia-inducible factor-2alpha. J Neurosci. 2009 Jun 3;29(22):7137-47. |
0(0,0,0,0) | Details |
| 19109944 | Ohtani M, Daly JW, Oka T: Co-existence of muscarinic and nicotinic receptors and their functional interaction in mouse Beta-TC6 cells. Eur J Pharmacol. 2009 Feb 14;604(1-3):150-7. Epub 2008 Dec 16. The maximal [Ca (2+)](i) response induced by carbamylcholine was larger than that of oxotremorine M or that of nicotine, suggesting that carbamylcholine enhanced the [Ca (2+)](i) response by stimulating two types of receptor. |
0(0,0,0,0) | Details |