| Name | cholinesterase |
|---|---|
| Synonyms | Acylcholine acylhydrolase; BCHE; BCHE protein; Butyrylcholine esterase; Butyrylcholinesterase; CHE1; Choline esterase II; Cholinesterase… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 20097188 | Lee S, Poet TS, Smith JN, Busby-Hjerpe AL, Timchalk C: Effect of in vivo nicotine exposure on chlorpyrifos pharmacokinetics and pharmacodynamics in rats. Chem Biol Interact. 2010 Mar 30;184(3):449-57. Epub 2010 Jan 25. The objective of this study was to evaluate the impact of repeated nicotine exposure on the pharmacokinetics of chlorpyrifos (CPF) and its major metabolite, 3,5,6-trichloro-2-pyridinol (TCPy) in blood and urine and also to determine the impact on cholinesterase (ChE) activity in plasma and brain. |
81(1,1,1,1) | Details |
| 19639304 | Masuoka T, Kamei C: The role of nicotinic receptors in the amelioration of cholinesterase inhibitors in -induced memory deficits. Psychopharmacology. 2009 Oct;206(2):259-65. Epub 2009 Jul 29. RATIONALE: Nicotine receptors in the brain are closely related with memory amelioration induced by cholinesterase inhibitors. |
34(0,1,1,4) | Details |
| 20078461 | Sofuoglu M: Cognitive enhancement as a pharmacotherapy target for stimulant addiction. Addiction. 2010 Jan;105(1):38-48. These include galantamine, and rivastigmine (cholinesterase inhibitors), varenicline (partial nicotine agonist), guanfacine (alpha (2)-adrenergic agonist) and atomoxetine (norepinephrine transporter inhibitor). |
31(0,1,1,1) | Details |
| 19255787 | Roszer T, Jozsa T, Szentmiklosi AJ, Banfalvi G: inhibits (NO) synthesis in the gastropod nervous system. Cell Tissue Res. 2009 May;336(2):325-35. Epub 2009 Mar 3. In rats, moderately elevates production, whereas the nicotinic receptor agonists (nicotine, acetyl thiocholine iodide, metacholine) and the cholinesterase inhibitor eserine reduce enteric formation in snails. |
31(0,1,1,1) | Details |
| 20107127 | Kozhemyakin M, Rajasekaran K, Kapur J: Central cholinesterase inhibition enhances glutamatergic synaptic transmission. J Neurophysiol. 2010 Jan 27. The nicotinic receptor antagonist alpha bungarotoxin did not block the effects of paraoxon; however, nicotine enhanced glutamatergic transmission. |
2(0,0,0,2) | Details |
| 19540221 | Munhoz E, De Lima TC, Souccar C, Lapa AJ, Lima-Landman MT: Allosteric interaction of the anticholinergic drug [N-(4-phenyl)-phenacyl-l-hyoscyamine] (Phenthonium) with nicotinic receptors of post-ganglionic sympathetic neurons of the rat vas deferens. Eur J Pharmacol. 2009 Aug 15;616(1-3):229-35. Epub 2009 Jun 18. Specifically, Phenthonium increases the spontaneous release of at the motor endplate without depolarizing the muscle or inhibiting cholinesterase activity. |
1(0,0,0,1) | Details |
| 19526284 | Das JR, Tizabi Y: Additive protective effects of and nicotine against -induced cytotoxicity in SH-SY5Y cells. Neurotox Res. 2009 Oct;16(3):194-204. Epub 2009 Mar 20. However, cholinesterase inhibitors may also directly interact with nicotinic receptors and possess neuroprotective properties. |
1(0,0,0,1) | Details |