| Name | CA1 |
|---|---|
| Synonyms | CA IX; CA1; Carbonic anhydrase I; CA2; CAII; Carbonic anhydrase II; Carbonic dehydratase; Carbonic anhydrase III… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19371581 | Hernandez-Morales M, Garcia-Colunga J: Effects of nicotine on K+ currents and nicotinic receptors in astrocytes of the hippocampal CA1 region. Neuropharmacology. 2009 May-Jun;56(6-7):975-83. Epub 2009 Feb 8. |
168(2,2,3,3) | Details |
| 19464074 | Srivareerat M, Tran TT, Salim S, Aleisa AM, Alkadhi KA: Chronic nicotine restores normal Abeta levels and prevents short-term memory and E-LTP impairment in Abeta rat model of Alzheimer's disease. Neurobiol Aging. 2009 May 20. The results indicate that 6 weeks of nicotine treatment reduced the levels of Abeta (1-40) and BACE1 peptides in hippocampal area CA1 and prevented Abeta-induced impairment of learning and short-term memory. |
162(2,2,2,2) | Details |
| 19442878 | Raval AP, Bhatt A, Saul I: Chronic nicotine exposure inhibits 17beta--mediated protection of the hippocampal CA1 region against cerebral ischemia in female rats. Neurosci Lett. 2009 Jul 17;458(2):65-9. Epub 2009 Apr 14. |
81(1,1,1,1) | Details |
| 20035769 | Rezayof A, Shirazi-Zand Z, Zarrindast MR, Nayer-Nouri T: Nicotine improves -induced memory impairment: the role of dorsal hippocampal NMDA receptors. Life Sci. 2010 Feb 13;86(7-8):260-6. Epub 2009 Dec 24. Moreover, intra-CA1 microinjection of MK-801 reversed the -induced potentiation of the nicotine response. |
13(0,0,2,3) | Details |
| 20058601 | Feng CS, Wang Y, Ma HC, Yue Y: [Role of central neuronal nicotinic receptor in the inhibitory effect of isoflurane on synaptic long-term potentiation in hippocampal slices of rats]. Zhonghua Yi Xue Za Zhi. 2009 Aug 18;89(31):2206-9. OBJECTIVE: To determine effect of central neuronal nicotinic receptor on synaptic long-term potentiation (LTP) in the CA1 area of rats hippocampal slices. Seventy-seven slices were randomly divided into 11 equal groups (n = 7 each): group LTP; group isoflurane 0.125; group isoflurane 0.25; group isoflurane 0.5; group nicotine 0.1; group nicotine 1.0; group nicotine 10.0; group nicotine 1.0 + isoflurane 0.25; group nicotine 10.0 + isoflurane 0.25; group mecamylamine; group mecamylamine + isoflurane 0.125. |
2(0,0,0,2) | Details |
| 19050173 | Dunlop J, Lock T, Jow B, Sitzia F, Grauer S, Jow F, Kramer A, Bowlby MR, Randall A, Kowal D, Gilbert A, Comery TA, Larocque J, Soloveva V, Brown J, Roncarati R: Old and new pharmacology: positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor by the (2B/C) receptor antagonist SB-206553 (3,5-dihydro-5-methyl-N-3-pyridinylbenzo [1,2-b:4,5-b'] di pyrrole-1 (2H)-carboxamide). J Pharmacol Exp Ther. 2009 Mar;328(3):766-76. Epub 2008 Dec 2. In a Ca2+ flux fluorometric imaging plate reader assay, SB-206553 (3,5-dihydro-5-methyl -N-3-pyridinylbenzo [1, 2-b:4,5 -b']-di pyrrole-1 (2H)-carboxamide), a compound known as a (2B/2C) receptor antagonist, produced an 8-fold potentiation of the evoked signal in the presence of an EC (20) concentration of nicotine and a corresponding EC (50) of 1.5 muM for potentiation of EC (20) nicotine responses in GH4C1 cells expressing the alpha7 receptor. Native nicotinic receptors in CA1 stratum radiatum interneurons of rat hippocampal slices could also be activated by (200 microM), an effect that was entirely blocked by the alpha7-selective antagonist methyllycaconitine (MLA). |
1(0,0,0,1) | Details |
| 19692619 | Tu B, Gu Z, Shen JX, Lamb PW, Yakel JL: Characterization of a nicotine-sensitive neuronal population in rat entorhinal cortex. J Neurosci. 2009 Aug 19;29(33):10436-48. |
0(0,0,0,0) | Details |
| 19576279 | Oliveira-da-Silva A, Vieira FB, Cristina-Rodrigues F, Filgueiras CC, Manhaes AC, Abreu-Villaca Y: Increased apoptosis and reduced neuronal and glial densities in the hippocampus due to nicotine and exposure in adolescent mice. Int J Dev Neurosci. 2009 Oct;27(6):539-48. Epub 2009 Jul 1. Considering the role of the hippocampus in both anxiety and memory/learning, we investigated whether adolescent nicotine and/or administration elicit apoptotic cell death and whether this results in neuronal and/or glial density alterations in the following regions of the hippocampus: granular layer of the dentate gyrus (GrDG), molecular layer (Mol), CA1, CA2 and CA3. |
7(0,0,1,2) | Details |
| 20138127 | Oliveira-da-Silva A, Manhaes AC, Cristina-Rodrigues F, Filgueiras CC, Abreu-Villaca Y: Hippocampal increased cell death and decreased cell density elicited by nicotine and/or during adolescence are reversed during drug withdrawal. Neuroscience. 2010 Apr 28;167(1):163-73. Epub 2010 Feb 4. In the present study, we investigated the effects of adolescent nicotine and/or withdrawal on the following regions of the hippocampus: Granular layer of the Dentate Gyrus (GrDG), Molecular layer (Mol), CA1, CA2 and CA3. |
6(0,0,1,1) | Details |
| 19410565 | Son JH, Winzer-Serhan UH: Chronic neonatal nicotine exposure increases mRNA expression of neurotrophic factors in the postnatal rat hippocampus. Brain Res. 2009 Jun 30;1278:1-14. Epub 2009 May 3. Specifically, BDNF mRNA expression, detected in CA1, CA3 stratum (s.) pyramidal and granule cell layer of the dentate gyrus (DG), was increased by 27.4%, 23.26% and 27.3%, respectively. |
3(0,0,0,3) | Details |
| 20153739 | Hunter RG, Bloss EB, McCarthy KJ, McEwen BS: Regulation of the nicotinic receptor alpha7 subunit by chronic stress and corticosteroids. Brain Res. 2010 Feb 11. The alpha7 subunit of the nicotinic acetylcholine receptor (NAchRalpha7) is one of the principal brain receptors for nicotine and is thought to be a mediator of nicotine's pro-cognitive effects. We found that CRS increased the levels of NAchRalpha7 mRNA in the CA1, CA3 and dentate gyrus while levels of the protein were lowered by the same treatment. |
1(0,0,0,1) | Details |
| 19936715 | Small E, Shah HP, Davenport JJ, Geier JE, Yavarovich KR, Yamada H, Sabarinath SN, Derendorf H, Pauly JR, Gold MS, Bruijnzeel AW: Tobacco smoke exposure induces nicotine dependence in rats. Psychopharmacology. 2010 Jan;208(1):143-58. Epub 2009 Nov 21. Tobacco smoke exposure increased the alpha7 nAChR density in the CA2/3 area and the stratum oriens and increased the non-alpha7 nAChR density in the dentate gyrus. RATIONALE: Tobacco smoke contains nicotine and many other compounds that act in concert on the brain reward system. |
1(0,0,0,1) | Details |
| 19170184 | Velez-Fort M, Audinat E, Angulo MC: Functional alpha 7-containing nicotinic receptors of NG2-expressing cells in the hippocampus. Glia. 2009 Aug 1;57(10):1104-14. We demonstrated that these cells express functional nAChRs during the second postnatal week, i.e., the period in which they become the most abundant proliferative cell type of CA1 stratum radiatum. In addition, nanomolar concentrations of nicotine, which did not induce any response in these cells, largely desensitized nAChR-mediated currents. |
1(0,0,0,1) | Details |
| 20004675 | Lagostena L, Danober L, Challal S, Lestage P, Mocaer E, Trocme-Thibierge C, Cherubini E: Modulatory effects of S 38232, a non alpha-7 containing nicotine acetylcholine receptor agonist on network activity in the mouse hippocampus. Neuropharmacology. 2010 Mar-Apr;58(4-5):806-15. Epub 2009 Dec 24. |
0(0,0,0,0) | Details |