Protein Information

Name cathepsin L
Synonyms CATL; MEP; CTSL; CTSL protein; Cathepsin L; Cathepsin L precursor; Cathepsin L splice variant; Major excreted protein…

Compound Information

Name nicotine
CAS

Reference List

PubMed Abstract RScore(About this table)
19372204 Biswas N, Rodriguez-Flores JL, Courel M, Gayen JR, Vaingankar SM, Mahata M, Torpey JW, Taupenot L, O'Connor DT, Mahata SK: Cathepsin L colocalizes with chromogranin a in chromaffin vesicles to generate active peptides. Endocrinology. 2009 Aug;150(8):3547-57. Epub 2009 Apr 16.

The pool of peptides generated from the CTSL cleavage of CgA inhibited nicotine-induced catecholamine secretion from PC12 cells.
92(1,1,1,12) Details