| Name | 5 HT 2A |
|---|---|
| Synonyms | 5 HT 2; 5 HT 2A; 5 HT2; 5 HT2A; 5 hydroxytryptamine (serotonin) receptor 2A; 5 hydroxytryptamine 2A receptor; 5 hydroxytryptamine receptor 2A; HTR 2… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19347958 | Zaniewska M, McCreary AC, Filip M: Interactions of serotonin (5-HT) 2 receptor-targeting ligands and nicotine: locomotor activity studies in rats. Synapse. 2009 Aug;63(8):653-61. |
194(2,3,3,4) | Details |
| 20196140 | Zaniewska M, McCreary AC, Wydra K, Filip M: Differential effects of (5-HT)(2) receptor-targeting ligands on locomotor responses to nicotine-repeated treatment. Synapse. 2010 Mar 1;64(7):511-519. We verified the hypothesis that (5-HT)(2) receptors control the locomotor effects of nicotine (0.4 mg kg (-1)) in rats by using the 5-HT (2A) receptor antagonist M100907, the preferential 5-HT (2A) receptor agonist DOI, the 5-HT (2C) receptor antagonist SB 242084, and the 5-HT (2C) receptor agonists Ro 60-0175 and WAY 163909. |
143(1,3,3,3) | Details |
| 19372687 | Slotkin TA, Seidler FJ: Nicotine exposure in adolescence alters the response of systems to nicotine administered subsequently in adulthood. Dev Neurosci. 2009;31(1-2):58-70. Epub 2009 Apr 17. We gave nicotine to adolescent rats (postnatal days, PD, 30-47), simulating plasma levels in smokers, and then examined the subsequent effects of nicotine given again in young adulthood (PD 90-107), focusing on 5-HT (1A) and 5-HT (2) receptors and the 5-HT transporter during nicotine treatment (PD 105) and withdrawal (PD 110, 120, 130), and long-term changes (PD 180). |
81(1,1,1,1) | Details |
| 20153341 | Zaniewska M, McCreary AC, Wydra K, Filip M: Effects of (5-HT)(2) receptor ligands on depression-like behavior during nicotine withdrawal. Neuropharmacology. 2010 Feb 11. This data set demonstrates that 5-HT (2A) receptor antagonist and 5-HT (2C) receptor agonists exhibited effects similar to antidepressant drugs and abolished the depression-like effects in nicotine-withdrawn rats. |
31(0,1,1,1) | Details |
| 19111403 | Polina ER, Contini V, Hutz MH, Bau CH: The 2A receptor gene in alcohol dependence and tobacco smoking. Drug Alcohol Depend. 2009 Apr 1;101(1-2):128-31. Epub 2008 Dec 25. The serotonin receptor gene HTR2A has been a candidate gene with some evidence for association with and nicotine dependencies. |
8(0,0,1,3) | Details |
| 19176807 | Lanteri C, Hernandez Vallejo SJ, Salomon L, Doucet EL, Godeheu G, Torrens Y, Houades V, Tassin JP: Inhibition of monoamine oxidases desensitizes 5-HT1A autoreceptors and allows nicotine to induce a neurochemical and behavioral sensitization. J Neurosci. 2009 Jan 28;29(4):987-97. |
0(0,0,0,0) | Details |