| Name | kappa opioid receptor |
|---|---|
| Synonyms | Kappa opioid receptor; KOR 1; KOR1; Kappa type opioid receptor; OPRK; OPRK 1; OPRK1; Opioid receptor kappa 1… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19804796 | Bruijnzeel AW: kappa-Opioid receptor signaling and brain reward function. . Brain Res Rev. 2009 Dec 11;62(1):127-46. Epub 2009 Oct 2. This might explain that in some studies kappa-opioid receptor agonists attenuate nicotine and opioid withdrawal symptomatology. |
82(1,1,1,2) | Details |
| 19806344 | McCarthy MJ, Zhang H, Neff NH, Hadjiconstantinou M: Nicotine withdrawal and kappa-opioid receptors. . Psychopharmacology. 2009 Oct 6. OBJECTIVES: This study aims to investigate the consequences of enhanced dynorphinergic activity on kappa-opioid receptor (KOPr) expression, coupling, and function in CPU and NAc following chronic nicotine administration and withdrawal. |
82(1,1,1,2) | Details |
| 20232057 | Jackson KJ, Carroll FI, Negus SS, Damaj MI: Effect of the selective kappa-opioid receptor antagonist JDTic on nicotine antinociception, reward, and withdrawal in the mouse. Psychopharmacology. 2010 Mar 16. |
32(0,1,1,2) | Details |
| 20170672 | Berrendero F, Robledo P, Trigo JM, Martin-Garcia E, Maldonado R: Neurobiological mechanisms involved in nicotine dependence and reward: Participation of the endogenous opioid system. Neurosci Biobehav Rev. 2010 Feb 16. An up-regulation of mu-opioid receptors has been reported after chronic nicotine treatment that could counteract the development of nicotine tolerance, whereas the down-regulation induced on kappa-opioid receptors seems to facilitate nicotine tolerance. |
6(0,0,1,1) | Details |