| Name | UGT2B10 |
|---|---|
| Synonyms | UDP glucuronosyltransferase transferase 2 family member B10; UDPGT; UDP glycosyltransferase 2 family member B10; UDP glycosyltransferase 2 family polypeptide B10; UDP glucuronosyltransferase 2B10; UDP glucuronosyltransferase 2B10 precursor; UGT2B10; Udp Glucuronosyltransferase 2B10 Precursor Microsomal… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19786624 | Berg JZ, Mason J, Boettcher AJ, Hatsukami DK, Murphy SE: Nicotine metabolism in African Americans and European Americans: variation in glucuronidation by ethnicity and UGT2B10 haplotype. J Pharmacol Exp Ther. 2010 Jan;332(1):202-9. Epub 2009 Sep 28. In a second study of smokers (n = 84), the relationship of a UGT2B10 haplotype linked with D67Y to nicotine and glucuronidation levels was determined. |
166(2,2,2,6) | Details |
| 20133892 | Zhou D, Guo J, Linnenbach AJ, Booth-Genthe CL, Grimm SW: Role of Human UGT2B10 in N-Glucuronidation of Tricyclic Antidepressants, Amitriptyline, Clomipramine and Trimipramine. Drug Metab Dispos. 2010 Feb 4. Nicotine was found to selectively inhibit UGT2B10 but not UGT1A4 activity. |
6(0,0,0,6) | Details |