| Name | CB1 receptor |
|---|---|
| Synonyms | Brain cannabinoid receptor 1; CNR1; CANN 6; CANN6; CB R; CB1; CB1 receptor; CB1A… |
| Name | nicotine |
|---|---|
| CAS |
| PubMed | Abstract | RScore(About this table) | |
|---|---|---|---|
| 19617654 | Biala G, Kruk M, Budzynska B: Effects of the cannabinoid receptor ligands on anxiety-related effects of d-amphetamine and nicotine in the mouse elevated plus maze test. J Physiol Pharmacol. 2009 Jun;60(2):113-22. The cannabinoid receptor ligands, WIN 55,212-2, a non-selective cannabinoid receptor agonist (0.25; 0.5 and 1 mg/kg, ip) and rimonabant, a CB1 cannabinoid receptor antagonist (0.25; 0.5; 1 and 2 mg/kg, ip) were injected prior to each injection of saline or acute and subchronic d-amphetamine or nicotine. |
31(0,1,1,1) | Details |
| 19540830 | Wing VC, Cagniard B, Murphy NP, Shoaib M: Measurement of affective state during chronic nicotine treatment and withdrawal by affective taste reactivity in mice: the role of endocannabinoids. Biochem Pharmacol. 2009 Oct 1;78(7):825-35. Epub 2009 Jun 21. In the second study, the endocannabinoid CB1-receptor antagonist AM251 (1, 3 and 10mg/kg, intraperitoneal) or vehicle was acutely administered before taste reactivity measurement during chronic nicotine administration. |
31(0,1,1,1) | Details |
| 19157986 | Knackstedt LA, Kalivas PW: and reinstatement. Curr Opin Pharmacol. 2009 Feb;9(1):59-64. Epub 2009 Jan 20. New molecular and neurochemical adaptations in the glutamatergic system which drive cocaine relapse have been identified, such as the ability of CB1 receptor stimulation to reduce basal levels and the involvement of the GluR1 receptor subunit in reinstatement. Furthermore, it is apparent that similar glutamatergic neuroadaptations arise after self-administration of cocaine, heroin, nicotine, and |
1(0,0,0,1) | Details |
| 20201816 | Maccioni P, Colombo G, Carai MA: Blockade of the cannabinoid CB1 receptor and alcohol dependence: preclinical evidence and preliminary clinical data. CNS Neurol Disord Drug Targets. 2010 Mar 1;9(1):55-9. Specifically, cannabinoid CB (1) receptor antagonists--including the prototype, rimonabant--have been reported to suppress: (a) acquisition and maintenance of drinking behavior under the 2-bottle vs water" choice regimen; (b) the increase in intake occurring after a period of abstinence (an experimental model of relapse); (c) alcohol's reinforcing and motivational properties measured in rats trained to perform a specific task (e.g., lever-pressing) to access (d) reinstatement of extinguished -seeking behavior triggered in rats by a nicotine challenge or presentation of cues previously associated to availability (another model of relapse). |
1(0,0,0,1) | Details |
| 19443943 | Budzynska B, Kruk M, Biala G: Effects of the cannabinoid CB1 receptor antagonist AM 251 on the reinstatement of nicotine-conditioned place preference by drug priming in rats. Pharmacol Rep. 2009 Mar-Apr;61(2):304-10. The aim of the present studies is to evaluate the role of CB1 cannabinoid receptors in the reinstatement of nicotine-induced conditioned place preference. |
224(2,4,4,4) | Details |
| 20331564 | Wing VC, Shoaib M: A second-order schedule of food reinforcement in rats to examine the role of CB1 receptors in the reinforcement-enhancing effects of nicotine. Addict Biol. 2010 Mar 10. The effect of the acute nicotine challenge (0.05, 0.1 and 0.2 mg/kg, s.c.) and the CB1 receptor antagonist AM251 (0.1, 0.3 and 1 mg/kg, intraperitoneal [i.p.]) on responding for the CS and/or UCS was examined. |
55(0,1,5,5) | Details |
| 20331563 | Wing VC, Shoaib M: Second-order schedules of nicotine reinforcement in rats: effect of AM251. Addict Biol. 2010 Mar 10. Nicotine and the CS were only able to independently maintain responding to similar level under the [FI 10' (FR3: S)] schedule, which was subsequently employed to examine the effects of the selective CB1 receptor antagonist AM251. |
37(0,1,2,2) | Details |
| 19463710 | Biala G, Budzynska B, Staniak N: Effects of rimonabant on the reinstatement of nicotine-conditioned place preference by drug priming in rats. Behav Brain Res. 2009 Sep 14;202(2):260-5. Epub 2009 Apr 8. Furthermore, the objective of the present study was to evaluate the efficacy of CB1 cannabinoid receptor antagonist rimonabant (0.5, 1 and 2mg/kg, i.p.) in blocking the reinstatement of nicotine-induced CPP provoked by nicotine and morphine. |
32(0,1,1,2) | Details |